SCHEMBL17867293

SCHEMBL17867293

O=C1NC(Cc2c[nH]c3ccccc23)C(=O)NC1Cc1ccccc1

nearest known ligand 0.72

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TACR2 P21452 16/20 0.72
IDO1 P14902 1/20 0.67
KMT2A Q03164 2/20 0.64
MEN1 O00255 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29701947 1.00 TACR2 (0.72) TACR2IDO1KMT2AMEN1
SCHEMBL29701948 1.00 TACR2 (0.72) TACR2IDO1KMT2AMEN1
SCHEMBL13399673 0.92 IDO1 (0.76) TACR2IDO1KMT2AMEN1
SCHEMBL2042419 0.92 IDO1 (0.76) TACR2IDO1KMT2AMEN1
SCHEMBL17867048 0.92 IDO1 (0.76) TACR2IDO1KMT2AMEN1
SCHEMBL14595068 0.92 IDO1 (0.76) TACR2IDO1KMT2AMEN1
SCHEMBL12809540 0.92 IDO1 (0.76) TACR2IDO1KMT2AMEN1
SCHEMBL31714574 0.89 IDO1 (0.61) TACR2IDO1
SCHEMBL29717273 0.89 IDO1 (0.61) TACR2IDO1
SCHEMBL12368076 0.87 KMT2A (0.60) TACR2IDO1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023077447-A1 CYCLOPEPTIDE GLASS AND PHARMACEUTICAL COMPOSITION GLASS CONTAINING CYCLOPEPTIDE 中国科学院过程工程研究所 2023-05-11 WO disclosed
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 US disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 US disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 US disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 US disclosed