SCHEMBL17867335

SCHEMBL17867335

Cc1ccc(O)c2c1C(=O)c1cccc(O)c1C2=O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 5/20 0.68
▸ ELANE P08246 4/20 0.68
▸ CTSG P08311 2/20 0.68
▸ MAPT P10636 6/20 0.66
▸ TDP1 Q9NUW8 6/20 0.66
▸ ALDH1A1 P00352 5/20 0.66
▸ HPGD P15428 5/20 0.66
▸ MAPK1 P28482 4/20 0.66
▸ ALOX15 P16050 4/20 0.66
▸ HSD17B10 Q99714 4/20 0.66
▸ SMN1; SMN2 Q16637 4/20 0.66
▸ TSHR P16473 3/20 0.66
▸ LMNA P02545 2/20 0.66
▸ MAOB P27338 2/20 0.66
▸ HTT P42858 1/20 0.66
▸ MEN1 O00255 7/20 0.58
▸ KMT2A Q03164 7/20 0.58
▸ KDM4E B2RXH2 4/20 0.58
▸ CYP3A4 P08684 4/20 0.58
▸ RECQL P46063 4/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9577702 0.89 EGFR (0.62) MAOAELANECTSGMAPTTDP1
SCHEMBL30695844 0.89 MAOA (0.86) MAOAELANECTSGMAPTTDP1
SCHEMBL3198327 0.89 MAOA (0.86) MAOAELANECTSGMAPTTDP1
SCHEMBL11103588 0.87 MEN1 (0.76) MAOAELANECTSGMAPTTDP1
SCHEMBL13239412 0.87 MAOA (0.76) MAOAELANECTSGMAPTTDP1
SCHEMBL23724036 0.85 MAPT (0.77) MAOAELANECTSGMAPTTDP1
SCHEMBL30241843 0.85 MAPT (0.77) MAOAELANECTSGMAPTTDP1
SCHEMBL13657177 0.84 CSNK2A2 (0.60) MAOAELANECTSGMAPTTDP1
SCHEMBL13881115 0.84 ELANE (0.50) MAOAELANECTSGMAPTTDP1
SCHEMBL13880670 0.84 ELANE (0.50) MAOAELANECTSGMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 — — US disclosed
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 — — US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 — — US disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 — — US disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 — — US disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 — — US disclosed
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