Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | GJB2 | P29033 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TACR2 | P21452 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | GJA1 | P17302 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17867755 | 1.00 | PDE4D (0.53) | PDE4DSLC6A2BCHEACHEGJB2 | |
| SCHEMBL24058165 | 0.92 | PDE4D (0.58) | PDE4DSLC6A2BCHEACHEGJB2 | |
| SCHEMBL31556052 | 0.92 | PDE4D (0.58) | PDE4DSLC6A2BCHEACHEGJB2 | |
| SCHEMBL18868663 | 0.88 | PDE4D (0.52) | PDE4DSLC6A2BCHEACHEGJB2 | |
| SCHEMBL11424925 | 0.88 | PDE4D (0.52) | PDE4DSLC6A2BCHEACHEGJB2 | |
| SCHEMBL18639181 | 0.88 | PDE4D (0.52) | PDE4DSLC6A2BCHEACHEGJB2 | |
| SCHEMBL17867766 | 0.88 | PDE4D (0.52) | PDE4DSLC6A2BCHEACHEGJB2 | |
| SCHEMBL18542094 | 0.88 | PDE4D (0.52) | PDE4DSLC6A2BCHEACHEGJB2 | |
| SCHEMBL22754536 | 0.88 | PDE4D (0.52) | PDE4DSLC6A2BCHEACHEGJB2 | |
| SCHEMBL24725536 | 0.88 | PDE4D (0.52) | PDE4DSLC6A2BCHEACHEGJB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11925654-B2 | Esters of 2-deoxy-monosaccharides with anti proliferative activity | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-03-12 | — | — | US | disclosed |
| US-20220023326-A1 | ESTERS OF 2-DEOXY-MONOSACCHARIDES WITH ANTI PROLIFERATIVE ACTIVITY | UNIV TEXAS (US) | 2022-01-27 | — | — | US | disclosed |
| EP-3939595-A1 | ESTERS OF 2-DEOXY-MONOSACCHARIDES WITH ANTI PROLIFERATIVE ACTIVITY | Board of Regents, The University of Texas System (US) | 2022-01-19 | — | — | EP | disclosed |
| US-11026960-B2 | Esters of 2-deoxy-monosaccharides with anti proliferative activity | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-06-08 | — | — | US | disclosed |
| US-20190224225-A1 | ESTERS OF 2-DEOXY-MONOSACCHARIDES WITH ANTI PROLIFERATIVE ACTIVITY | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2019-07-25 | — | — | US | disclosed |
| US-10201554-B2 | Esters of 2-deoxy-monosacharides with anti proliferative activity | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-02-12 | — | — | US | disclosed |
| US-20160184336-A1 | ESTERS OF 2-DEOXY-MONOSACHARIDES WITH ANTI PROLIFERATIVE ACTIVITY | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10201554-B2 | Esters of 2-deoxy-monosacharides with anti proliferative activity | DERA, G6PD, HK2 | PDE4D 2119/4885SLC6A2 1908/4885BCHE 1766/4885 |
| US-11925654-B2 | Esters of 2-deoxy-monosaccharides with anti proliferative activity | SLC2A2, SLC2A1, SLC2A4 | PDE4D 2417/4885SLC6A2 1756/4885BCHE 2329/4885 |
| US-20190224225-A1 | ESTERS OF 2-DEOXY-MONOSACCHARIDES WITH ANTI PROLIFERATIVE ACTIVITY | SLC2A2, SLC2A1, SLC2A4 | PDE4D 2417/4885SLC6A2 1756/4885BCHE 2329/4885 |
| US-11026960-B2 | Esters of 2-deoxy-monosaccharides with anti proliferative activity | SLC2A2, SLC2A1, SLC2A4 | PDE4D 2417/4885SLC6A2 1756/4885BCHE 2329/4885 |
| US-20160184336-A1 | ESTERS OF 2-DEOXY-MONOSACHARIDES WITH ANTI PROLIFERATIVE ACTIVITY | DERA, G6PD, HK2 | PDE4D 2119/4885SLC6A2 1908/4885BCHE 1766/4885 |
| US-20220023326-A1 | ESTERS OF 2-DEOXY-MONOSACCHARIDES WITH ANTI PROLIFERATIVE ACTIVITY | SLC2A2, SLC2A1, SLC2A4 | PDE4D 2417/4885SLC6A2 1756/4885BCHE 2329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.