Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 3/20 | 0.45 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.44 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.44 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.44 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.44 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
| ▸ | GJB2 | P29033 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.41 |
| ▸ | CDC25B | P30305 | 5/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17867746 | 0.96 | TACR2 (0.45) | TACR2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL17867749 | 0.93 | SSTR1 (0.41) | TACR2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL17867761 | 0.92 | TACR2 (0.44) | TACR2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL17867747 | 0.88 | TACR2 (0.44) | TACR2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL21176708 | 0.88 | TACR2 (0.44) | TACR2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL9094454 | 0.86 | NT5E (0.46) | TACR2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL9094458 | 0.86 | NT5E (0.46) | TACR2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL17867760 | 0.85 | SSTR1 (0.40) | TACR2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL17867735 | 0.85 | TACR2 (0.44) | TACR2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL17867734 | 0.85 | TACR2 (0.44) | TACR2SSTR1SSTR2SSTR4SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10201554-B2 | Esters of 2-deoxy-monosacharides with anti proliferative activity | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-02-12 | — | — | US | disclosed |
| US-20160184336-A1 | ESTERS OF 2-DEOXY-MONOSACHARIDES WITH ANTI PROLIFERATIVE ACTIVITY | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10201554-B2 | Esters of 2-deoxy-monosacharides with anti proliferative activity | DERA, G6PD, HK2 | TACR2 4691/4885SSTR1 2920/4885SSTR2 1978/4885 |
| US-20160184336-A1 | ESTERS OF 2-DEOXY-MONOSACHARIDES WITH ANTI PROLIFERATIVE ACTIVITY | DERA, G6PD, HK2 | TACR2 4691/4885SSTR1 2920/4885SSTR2 1978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.