Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | TACR2 | P21452 | 2/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | CA9 | Q16790 | 4/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | PRKCG | P05129 | 1/20 | 0.35 |
| ▸ | PRKCB | P05771 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | PRKCH | P24723 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17867795 | 1.00 | TNF (0.39) | TNFTACR2KLK7KLK5CYP2D6 | |
| SCHEMBL17867753 | 0.85 | TNF (0.41) | TNFTACR2ALDH1A1MAPK1CA12 | |
| SCHEMBL17867752 | 0.85 | TNF (0.41) | TNFTACR2ALDH1A1MAPK1CA12 | |
| SCHEMBL17867770 | 0.83 | BCHE (0.43) | TNFTACR2ALDH1A1MAPK1CA12 | |
| SCHEMBL17867771 | 0.83 | BCHE (0.43) | TNFTACR2ALDH1A1MAPK1CA12 | |
| SCHEMBL17867811 | 0.82 | TNF (0.43) | TNFTACR2CYP2D6ALDH1A1MAPK1 | |
| SCHEMBL17867722 | 0.81 | TACR2 (0.39) | TNFTACR2CYP2D6ALDH1A1MAPK1 | |
| SCHEMBL17867754 | 0.79 | TACR2 (0.38) | TNFTACR2KLK7KLK5CYP2D6 | |
| SCHEMBL17867726 | 0.77 | TACR2 (0.39) | TNFTACR2ALDH1A1MAPK1CA1 | |
| SCHEMBL16155609 | 0.77 | PRKD3 (0.50) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11925654-B2 | Esters of 2-deoxy-monosaccharides with anti proliferative activity | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-03-12 | — | — | US | disclosed |
| US-20220023326-A1 | ESTERS OF 2-DEOXY-MONOSACCHARIDES WITH ANTI PROLIFERATIVE ACTIVITY | UNIV TEXAS (US) | 2022-01-27 | — | — | US | disclosed |
| EP-3939595-A1 | ESTERS OF 2-DEOXY-MONOSACCHARIDES WITH ANTI PROLIFERATIVE ACTIVITY | Board of Regents, The University of Texas System (US) | 2022-01-19 | — | — | EP | disclosed |
| US-11026960-B2 | Esters of 2-deoxy-monosaccharides with anti proliferative activity | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-06-08 | — | — | US | disclosed |
| US-20190224225-A1 | ESTERS OF 2-DEOXY-MONOSACCHARIDES WITH ANTI PROLIFERATIVE ACTIVITY | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2019-07-25 | — | — | US | disclosed |
| US-10201554-B2 | Esters of 2-deoxy-monosacharides with anti proliferative activity | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-02-12 | — | — | US | disclosed |
| US-20160184336-A1 | ESTERS OF 2-DEOXY-MONOSACHARIDES WITH ANTI PROLIFERATIVE ACTIVITY | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10201554-B2 | Esters of 2-deoxy-monosacharides with anti proliferative activity | DERA, G6PD, HK2 | TNF 3759/4885TACR2 4691/4885KLK7 1722/4885 |
| US-11925654-B2 | Esters of 2-deoxy-monosaccharides with anti proliferative activity | SLC2A2, SLC2A1, SLC2A4 | TNF 3445/4885TACR2 4635/4885KLK7 1956/4885 |
| US-20190224225-A1 | ESTERS OF 2-DEOXY-MONOSACCHARIDES WITH ANTI PROLIFERATIVE ACTIVITY | SLC2A2, SLC2A1, SLC2A4 | TNF 3445/4885TACR2 4635/4885KLK7 1956/4885 |
| US-11026960-B2 | Esters of 2-deoxy-monosaccharides with anti proliferative activity | SLC2A2, SLC2A1, SLC2A4 | TNF 3445/4885TACR2 4635/4885KLK7 1956/4885 |
| US-20160184336-A1 | ESTERS OF 2-DEOXY-MONOSACHARIDES WITH ANTI PROLIFERATIVE ACTIVITY | DERA, G6PD, HK2 | TNF 3759/4885TACR2 4691/4885KLK7 1722/4885 |
| US-20220023326-A1 | ESTERS OF 2-DEOXY-MONOSACCHARIDES WITH ANTI PROLIFERATIVE ACTIVITY | SLC2A2, SLC2A1, SLC2A4 | TNF 3445/4885TACR2 4635/4885KLK7 1956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.