Benzoic Acid

Benzoic Acid

SCHEMBL1786785

CC(C)CC(O)C(C)(C)O.O=C(O)c1ccccc1.O=C(O)c1ccccc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D

The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.47
TSHR P16473 1/20 0.47
NAPRT Q6XQN6 1/20 0.47
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
SRD5A2 P31213 1/20 0.41
KMT2A Q03164 1/20 0.40
MAPK1 P28482 1/20 0.38
FOLH1 Q04609 1/20 0.38
CTSL P07711 2/20 0.38
CTSB P07858 1/20 0.38
CTSS P25774 1/20 0.38
CTSK P43235 1/20 0.38
CYP2C8 P10632 1/20 0.38
CYP2C9 P11712 1/20 0.38
PSMB5 P28074 3/20 0.37
ADRB2 P07550 1/20 0.37
ADRB1 P08588 1/20 0.37
ADRB3 P13945 1/20 0.37
PSMB8 P28062 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoic Acid SCHEMBL1784503 0.83 TSHR (0.50) DAOTSHRNAPRTCES2CES1
Benzoic Acid SCHEMBL5085502 0.82 TSHR (0.58) DAOTSHRNAPRTCES2CES1
Benzoic Acid SCHEMBL1787177 0.81 TSHR (0.48) DAOTSHRNAPRTCES2CES1
Benzoic Acid SCHEMBL28685385 0.81 TSHR (0.52) DAOTSHRNAPRTCES2CES1
Benzoic Acid SCHEMBL1784532 0.80 TSHR (0.47) DAOTSHRNAPRTCES2CES1
Benzoic Acid SCHEMBL569416 0.79 TSHR (0.54) DAOTSHRNAPRTCES2CES1
Benzoic Acid SCHEMBL1782983 0.79 TSHR (0.54) DAOTSHRNAPRTCES2CES1
Benzoic Acid SCHEMBL1786860 0.79 TSHR (0.54) DAOTSHRNAPRTCES2CES1
Benzoic Acid SCHEMBL569454 0.78 TSHR (0.48) DAOTSHRNAPRTCES2CES1
Benzoic Acid SCHEMBL4837055 0.77 TSHR (0.52) DAOTSHRNAPRTCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050239636-A1 Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-10-27 US claimed
EP-3486263-A2 SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE W.R. Grace & CO. - CONN. (US) 2019-05-22 EP disclosed
EP-2185600-B1 SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE GRACE W R & CO (US) 2018-10-31 EP disclosed
US-9796796-B2 Self-limiting catalyst composition with No silane W. R. GRACE & CO.-CONN. (US) 2017-10-24 US disclosed
EP-1666505-B1 CATALYST COMPONENTS CATALYSTS FOR OLEFINIC POLYMERIZATION AND THE USE THEREOF CHINA PETROLEUM & CHEMICAL (CN) 2016-03-23 EP disclosed
CN-103087222-A Olefin polymerization catalyst, process for producing olefin polymer, polypropylene resin composition and article comprising the same SUMITOMO CHEMICAL CO 2013-05-08 CN disclosed
US-20130109789-A1 OLEFIN POLYMERIZATION CATALYST, PROCESS FOR PRODUCING OLEFIN POLYMER, POLYPROPYLENE RESIN COMPOSITION AND ARTICLE COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-02 US disclosed
US-20110124491-A1 Self-Limiting Catalyst Composition with No Silane W. R. GRACE & CO.-CONN. 2011-05-26 US disclosed
EP-2185600-A1 SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE Dow Global Technologies Inc. (US) 2010-05-19 EP disclosed
CN-101565475-A Catalyst component and catalyst thereof for olefinic polymerization CHINA PETROLEUM & CHEMICAL (CN) 2009-10-28 CN disclosed
US-7388061-B2 Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-06-17 US disclosed
US-7332455-B2 Catalyst component and catalyst for olefin polymerization as well as use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-02-19 US disclosed
CN-1310963-C Catalyst component for olefin polymerization reaction and catalyst CHINA PETROCHEMICAL CORP (CN) 2007-04-18 CN disclosed
EP-1666505-A1 CATALYST COMPONENTS CATALYSTS FOR OLEFINIC POLYMERIZATION AND THE USE THEREOF China Petroleum & Chemical Corporation (CN) 2006-06-07 EP disclosed
CN-1743348-A Catalyst component for olefinic polymerization and its catalyst CHINA PETROCHEMICAL CORP (CN) 2006-03-08 CN disclosed
CN-1743346-A Catalyst component for olefinic polymerization and its catalyst CHINA PETROCHEMICAL CORP (CN) 2006-03-08 CN disclosed
US-20050239636-A1 Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-10-27 US disclosed
US-20050119427-A1 Catalyst component and catalyst for olefin polymerization as well as use thereof BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-06-02 US disclosed
CN-1552741-A Catalyst component for olefin polymerization reaction and catalyst 中国石油化工股份有限公司 2004-12-08 CN disclosed
CN-1446197-A Oxygenated esters of 4-iodo phenylamino benzhydroxamic acids WARNER LAMBERT CO (US) 2003-10-01 CN disclosed