Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | DAO | P14920 | 1/20 | 0.54 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoyl Formic Acid SCHEMBL16045666 | 0.92 | CES2 (0.48) | TSHRDAONAPRTSRD5A2CES1 | |
| Benzoic Acid SCHEMBL569454 | 0.91 | TSHR (0.48) | TSHRDAONAPRTSRD5A2CES1 | |
| Benzoic Acid SCHEMBL27925082 | 0.90 | DAO (0.47) | TSHRDAONAPRTSRD5A2CES1 | |
| Benzoic Acid SCHEMBL1073180 | 0.88 | TSHR (0.45) | TSHRDAONAPRTSRD5A2CES1 | |
| Benzoic Acid SCHEMBL16048140 | 0.87 | TSHR (0.47) | TSHRDAONAPRTSRD5A2CES1 | |
| Benzoic Acid SCHEMBL16045947 | 0.87 | TSHR (0.41) | TSHRDAONAPRTSRD5A2CES1 | |
| Benzoic Acid SCHEMBL15542497 | 0.85 | TSHR (0.42) | TSHRDAONAPRTSRD5A2CES1 | |
| Benzoic Acid SCHEMBL1070689 | 0.79 | TSHR (0.52) | TSHRDAONAPRTSRD5A2CES1 | |
| Benzoic Acid SCHEMBL1786785 | 0.79 | DAO (0.47) | TSHRDAONAPRTSRD5A2CES1 | |
| Benzoic Acid SCHEMBL7999427 | 0.79 | TSHR (0.78) | TSHRDAONAPRTSRD5A2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113754801-B | Solid catalyst for preparing olefin polymer and solid catalyst system | 中国石油化工股份有限公司 | 2023-02-28 | — | — | CN | claimed |
| CN-113754803-B | Catalyst system and application thereof as catalyst for olefin polymerization | 中国石油化工股份有限公司 | 2023-02-24 | — | — | CN | claimed |
| CN-114426599-A | Catalyst component for preparing polyolefin, preparation method thereof, olefin polymerization catalyst and application thereof | 中国石油化工股份有限公司 | 2022-05-03 | — | — | CN | claimed |
| CN-113754801-A | Solid catalyst for preparing olefin polymer and solid catalyst system | 中国石油化工股份有限公司 | 2021-12-07 | — | — | CN | claimed |
| CN-113754803-A | Catalyst system and application thereof as catalyst for olefin polymerization | 中国石油化工股份有限公司 | 2021-12-07 | — | — | CN | claimed |
| EP-1472293-B1 | SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF | CHINA PETROLEUM & CHEM CORP (CN) | 2017-04-26 | — | — | EP | claimed |
| CN-104558293-B | Catalyst component for olefin polymerization and catalyst | 中国石油化工股份有限公司 | 2017-02-15 | — | — | CN | claimed |
| CN-104558293-A | Catalyst component for olefin polymerization and catalyst | CHINA PETROLEUM & CHEMICAL | 2015-04-29 | — | — | CN | claimed |
| US-7388061-B2 | Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2008-06-17 | — | — | US | claimed |
| US-20050239636-A1 | Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2005-10-27 | — | — | US | claimed |
| US-20050096389-A1 | Polyol ester compounds useful in preparation of a catalyst for olefins polymerization, process for preparing the same and use thereof | CHINA PETROLEUM & CHEMICAL (CN) | 2005-05-05 | — | — | US | claimed |
| CN-1580034-A | Glycol ester compound for preparing catalyst for olefinic polymerization | CHINA PETROCHEMICAL CORP (CN) | 2005-02-16 | — | — | CN | claimed |
| US-11840508-B2 | Catalyst system for olefin polymerization and use thereof | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2023-12-12 | — | — | US | disclosed |
| CN-113754802-B | Catalyst system for olefin polymerization reaction and prepolymerization catalyst composition | 中国石油化工股份有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-112300311-B | Catalyst for olefin polymerization and olefin polymerization method | 中国石油化工股份有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-113754801-B | Solid catalyst for preparing olefin polymer and solid catalyst system | 中国石油化工股份有限公司 | 2023-02-28 | — | — | CN | disclosed |
| CN-1453298-A | Catalyst for olefine polymerizing reaction and its components | CHINA PETROCHEMICAL CORP (CN) | 2003-11-05 | — | — | CN | disclosed |
| CN-1446197-A | Oxygenated esters of 4-iodo phenylamino benzhydroxamic acids | WARNER LAMBERT CO (US) | 2003-10-01 | — | — | CN | disclosed |
| WO-2003068828-A1 | SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2003-08-21 | — | — | WO | disclosed |
| WO-2003068723-A1 | POLYOL ESTER COMPOUNDS USEFUL IN PREPARATION OF A CATALYST FOR OLEFINS POLYMERIZATION, PROCESS FOR PREPARING THE SAME AND USE THEREOF | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2003-08-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11840508-B2 | Catalyst system for olefin polymerization and use thereof | SQSTM1, SAMM50, HPD | TSHR 4688/4885DAO 3774/4885NAPRT 3004/4885 |
| US-20050096389-A1 | Polyol ester compounds useful in preparation of a catalyst for olefins polymerization, process for preparing the same and use thereof | CBR3, CBR1, OXER1 | TSHR 921/4885DAO 1971/4885NAPRT 1682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.