SCHEMBL1786879

SCHEMBL1786879

COC1O[C@H](CCP(=O)(O)O)[C@@H](O)[C@H](O)[C@@H]1O

nearest known ligand 0.64

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
IGF2R P11717 4/20 0.64
G6PD P11413 4/20 0.44
M6PR P20645 1/20 0.41
CA1 P00915 3/20 0.40
CA2 P00918 3/20 0.40
CA9 Q16790 3/20 0.40
P2RY2 P41231 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25499079 1.00 IGF2R (0.64) IGF2RG6PDM6PRCA1CA2
SCHEMBL21711050 1.00 IGF2R (0.64) IGF2RG6PDM6PRCA1CA2
SCHEMBL29323828 0.89 IGF2R (0.51) IGF2RG6PDM6PRCA1CA2
SCHEMBL2609683 0.84 IGF2R (0.74) IGF2RCA1CA2CA9P2RY2
SCHEMBL23743570 0.84 IGF2R (0.69) IGF2RCA1CA2CA9P2RY2
SCHEMBL10291466 0.83 IGF2R (0.46) IGF2RG6PDM6PRCA1CA2
SCHEMBL25494488 0.83 IGF2R (0.59) IGF2RCA1CA2CA9P2RY2
SCHEMBL25495348 0.83 IGF2R (0.59) IGF2RCA1CA2CA9P2RY2
SCHEMBL26951662 0.83 IGF2R (0.59) IGF2RP2RY2
SCHEMBL2609674 0.81 IGF2R (0.74) IGF2RCA1CA2CA9P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2285817-B1 NOVEL USES OF D-MANNOPYRANOSE DERIVATIVES ACTIVATING ANGIOGENESIS CENTRE NAT RECH SCIENT (FR) 2012-08-01 EP claimed
US-20110124558-A1 NOVEL USES OF D-MANNOPYRANOSE DERIVATIVES ACTIVATING ANGIOGENESIS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2011-05-26 US claimed
US-8551960-B2 Uses of D-mannopyranose derivatives activating angiogenesis CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2013-10-08 US disclosed
US-20110124558-A1 NOVEL USES OF D-MANNOPYRANOSE DERIVATIVES ACTIVATING ANGIOGENESIS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2011-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110124558-A1 NOVEL USES OF D-MANNOPYRANOSE DERIVATIVES ACTIVATING ANGIOGENESIS MAN2A1, MANBA, MAN2B2 IGF2R 162/4885G6PD 71/4885M6PR 329/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.