SCHEMBL2609683

SCHEMBL2609683

COCCOC1OC(CCP(=O)(O)O)C(O)C(O)C1O

nearest known ligand 0.74

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
IGF2R P11717 8/20 0.74
P2RY2 P41231 2/20 0.36
CA1 P00915 3/20 0.35
CA2 P00918 3/20 0.35
CA9 Q16790 3/20 0.35
LGALS8 O00214 1/20 0.33
LGALS3 P17931 1/20 0.33
LGALS4 P56470 1/20 0.33
FBP1 P09467 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2609680 0.90 IGF2R (0.69) IGF2RP2RY2LGALS8LGALS3LGALS4
SCHEMBL2609674 0.88 IGF2R (0.74) IGF2RP2RY2CA1CA2CA9
SCHEMBL16518075 0.87 IGF2R (0.77) IGF2RP2RY2CA1CA2CA9
SCHEMBL23723835 0.87 IGF2R (0.77) IGF2RP2RY2CA1CA2CA9
SCHEMBL12944281 0.87 IGF2R (0.77) IGF2RP2RY2CA1CA2CA9
SCHEMBL22895179 0.85 IGF2R (1.00) IGF2RP2RY2CA1CA2CA9
SCHEMBL23743570 0.85 IGF2R (0.69) IGF2RP2RY2CA1CA2CA9
SCHEMBL2609676 0.85 IGF2R (0.69) IGF2RCA1CA2CA9LGALS8
SCHEMBL21711050 0.84 IGF2R (0.64) IGF2RP2RY2CA1CA2CA9
SCHEMBL1786879 0.84 IGF2R (0.64) IGF2RP2RY2CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8962573-B2 Compounds targeting the cation-independent mannose 6-phosphate receptor INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) 2015-02-24 US disclosed
US-20120093795-A1 COMPOUNDS TARGETING THE CATION-INDEPENDENT MANNOSE 6-PHOSPHATE RECEPTOR INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) 2012-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120093795-A1 COMPOUNDS TARGETING THE CATION-INDEPENDENT MANNOSE 6-PHOSPHATE RECEPTOR M6PR, IGF2R, MPI IGF2R 2/4885P2RY2 205/4885CA1 1995/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.