⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28007302 | 0.98 | MAPT (0.56) | — | |
| Hydrochloric Acid SCHEMBL3612344 | 0.79 | GAA (0.55) | — | |
| SCHEMBL1009206 | 0.79 | NPSR1 (0.86) | — | |
| SCHEMBL29650380 | 0.79 | NPSR1 (0.86) | — | |
| SCHEMBL6694995 | 0.79 | GAA (0.65) | — | |
| SCHEMBL2479722 | 0.78 | GAA (0.60) | — | |
| Water SCHEMBL8601146 | 0.77 | NPSR1 (0.82) | — | |
| SCHEMBL29697291 | 0.77 | — | — | |
| SCHEMBL9158496 | 0.77 | NPSR1 (0.82) | — | |
| SCHEMBL306337 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103041855-B | Preparation method of catalysts for dichloro-pyridine oxynitride | SHANGHAI NOVEL CHEMICAL TECHNOLOGY CO LTD | 2014-09-10 | — | — | CN | claimed |
| US-12018030-B2 | Pyrrolo and pyrazolopyrimidines as ubiquitin-specific protease 7 inhibitors | VALO HEALTH, INC. (US) | 2024-06-25 | — | — | US | disclosed |
| US-20210332052-A1 | PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS | VALO HEALTH, INC. | 2021-10-28 | — | — | US | disclosed |
| US-10934299-B2 | Pyrrolo and pyrazolopyrimidines as ubiquitin-specific protease 7 inhibitors | VALO EARLY DISCOVERY, INC. (US) | 2021-03-02 | — | — | US | disclosed |
| CN-110483423-A | P2X4 receptor antagonist | NIPPON CHEMIPHAR CO | 2019-11-22 | — | — | CN | disclosed |
| CN-110294757-A | A kind of copper catalysis one kettle way prepares the synthetic method and application of C-3 thiocarbamoyl imidazoles and pyridine derivatives | 青岛科技大学 | 2019-10-01 | — | — | CN | disclosed |
| CN-110256258-A | A method of photocatalytic synthesis is at more bromoaniline compounds in water phase | 福建医科大学 | 2019-09-20 | — | — | CN | disclosed |
| CN-110195237-A | A method of using bromide as bromating agent, the electro-catalysis in water phase prepares more bromoaniline compounds | 福建医科大学 | 2019-09-03 | — | — | CN | disclosed |
| CN-110183373-A | A kind of optical activity 1- (hetero) aryl indole derivatives and its preparation method and application | 浙江大学 | 2019-08-30 | — | — | CN | disclosed |
| US-10377760-B2 | Pyrrolo and pyrazolopyrimidines as ubiquitin-specific protease 7 inhibitors | FORMA THERAPEUTICS, INC. (US) | 2019-08-13 | — | — | US | disclosed |
| CN-103209960-A | Sulfonamide compounds useful as CYP17 inhibitors | BRISTOL MYERS SQUIBB CO | 2013-07-17 | — | — | CN | disclosed |
| CN-101395147-B | 1- (benzo [ D ] [1,3] dioxol-5-yl) -N- (phenyl) cyclopropane-carboxamide derivatives and related compounds as modulators of ATP-binding cassette transporters for the treatment of cystic fibrosis | VERTEX PHARMA | 2013-05-29 | — | — | CN | disclosed |
| CN-102958932-A | 5-HT receptor modulators and methods of use thereof | ABBVI INC | 2013-03-06 | — | — | CN | disclosed |
| CN-102762226-A | Benzonaphthyridine-containing vaccines | NOVARTIS AG | 2012-10-31 | — | — | CN | disclosed |
| CN-102464654-A | Novel antivirus compound | SHANGHAI HONGBO ZHIYUAN MEDICAL TECHNOLOGY CO LTD | 2012-05-23 | — | — | CN | disclosed |
| CN-102015651-A | Compounds and compositions as TLR activity modulators | IRM LLC | 2011-04-13 | — | — | CN | disclosed |
| CN-101981036-A | Pyrrolo [2, 3-D] pyridines and use thereof as tyrosine kinase inhibitors | NOVARTIS AG | 2011-02-23 | — | — | CN | disclosed |
| CN-101970572-A | Photocurable composition | SEKISUI CHEMICAL CO LTD | 2011-02-09 | — | — | CN | disclosed |
| CN-101743224-A | 7-substituted indole mcl-1 inhibitors | ABBOTT LAB | 2010-06-16 | — | — | CN | disclosed |
| CN-101641014-A | Poly (ADP-ribose) polymerase inhibitors | ABBOTT LAB US | 2010-02-03 | — | — | CN | disclosed |