Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 5/20 | 0.33 |
| ▸ | CTSK | P43235 | 4/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | PYGL | P06737 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17870273 | 1.00 | GRN (0.36) | GRNSORT1CTSSCTSKCTSL | |
| SCHEMBL17870438 | 0.89 | GRN (0.37) | GRNSORT1CTSSCTSKCTSL | |
| SCHEMBL17870440 | 0.89 | GRN (0.37) | GRNSORT1CTSSCTSKCTSL | |
| SCHEMBL17870455 | 0.77 | CAPN1 (0.47) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL17870456 | 0.77 | CAPN1 (0.47) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL23805208 | 0.74 | GRN (0.41) | GRNSORT1CTSSCTSKCTSL | |
| SCHEMBL23805209 | 0.74 | GRN (0.41) | GRNSORT1CTSSCTSKCTSL | |
| SCHEMBL17870150 | 0.74 | CTSS (0.35) | CTSSCTSKPYGLCYP2C9 | |
| SCHEMBL18515857 | 0.73 | GRN (0.56) | GRNSORT1PYGLCYP2C9 | |
| SCHEMBL17870521 | 0.73 | CTSS (0.43) | CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180265547-A1 | Z-SELECTIVE OLEFIN METATHESIS OF PEPTIDES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2018-09-20 | — | — | US | disclosed |
| US-20160185821-A1 | Z-SELECTIVE OLEFIN METATHESIS OF PEPTIDES | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185821-A1 | Z-SELECTIVE OLEFIN METATHESIS OF PEPTIDES | QPCT, PTMS, MAX | GRN 2486/4885SORT1 422/4885CTSS 203/4885 |
| US-20180265547-A1 | Z-SELECTIVE OLEFIN METATHESIS OF PEPTIDES | QPCT, PTMS, MAX | GRN 2486/4885SORT1 422/4885CTSS 203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.