Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.31 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6363593 | 0.87 | USP2 (0.36) | ALDH1A1CYP2D6CYP2C19USP2TSHR | |
| SCHEMBL17870512 | 0.85 | CYP2D6 (0.32) | ALDH1A1MAPTCYP2D6CYP2C19USP2 | |
| SCHEMBL17870511 | 0.85 | CYP2D6 (0.32) | ALDH1A1MAPTCYP2D6CYP2C19USP2 | |
| SCHEMBL17870446 | 0.81 | CTSS (0.39) | CNR1SMN1; SMN2ECE1KMT2AMAPK1 | |
| SCHEMBL25327830 | 0.80 | KMT2A (0.50) | ALDH1A1MAPTCNR1CYP2D6CYP2C19 | |
| SCHEMBL17870476 | 0.79 | CAPN1 (0.49) | ALDH1A1MAPTCYP2C19USP2TSHR | |
| SCHEMBL15791951 | 0.78 | CYP2D6 (0.35) | ALDH1A1CYP2D6CYP2C19USP2TSHR | |
| SCHEMBL17884298 | 0.76 | KMT2A (0.51) | CYP2D6MEN1KMT2ACAPN1CTSB | |
| SCHEMBL17884287 | 0.76 | KMT2A (0.51) | CYP2D6MEN1KMT2ACAPN1CTSB | |
| SCHEMBL15792286 | 0.75 | CYP2D6 (0.39) | ALDH1A1MAPTCYP2D6CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180265547-A1 | Z-SELECTIVE OLEFIN METATHESIS OF PEPTIDES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2018-09-20 | — | — | US | disclosed |
| US-20160185821-A1 | Z-SELECTIVE OLEFIN METATHESIS OF PEPTIDES | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185821-A1 | Z-SELECTIVE OLEFIN METATHESIS OF PEPTIDES | QPCT, PTMS, MAX | ALDH1A1 4444/4885MAPT 794/4885CNR1 3942/4885 |
| US-20180265547-A1 | Z-SELECTIVE OLEFIN METATHESIS OF PEPTIDES | QPCT, PTMS, MAX | ALDH1A1 4444/4885MAPT 794/4885CNR1 3942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.