Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 2/20 | 0.37 |
| ▸ | ACE | P12821 | 2/20 | 0.37 |
| ▸ | CPA1 | P15085 | 2/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17870458 | 0.86 | CTSS (0.37) | CTSSCTSKCA2KMT2ASMN1; SMN2 | |
| SCHEMBL17870460 | 0.86 | CTSS (0.37) | CTSSCTSKCA2KMT2ASMN1; SMN2 | |
| SCHEMBL17884325 | 0.81 | CTSS (0.63) | CTSSCTSKHTTALDH1A1KDM4E | |
| SCHEMBL25328927 | 0.81 | CTSS (0.44) | CTSSCTSKHTTALDH1A1ANPEP | |
| SCHEMBL17870511 | 0.79 | CYP2D6 (0.32) | ALDH1A1MMEACECPA1ACE2 | |
| SCHEMBL17870512 | 0.79 | CYP2D6 (0.32) | ALDH1A1MMEACECPA1ACE2 | |
| SCHEMBL16284115 | 0.79 | CTSS (0.48) | CTSSCTSKHTTALDH1A1ANPEP | |
| SCHEMBL17870150 | 0.77 | CTSS (0.35) | CTSSCTSK | |
| SCHEMBL25198620 | 0.77 | EPHX1 (0.50) | L3MBTL1SMN1; SMN2 | |
| SCHEMBL25265258 | 0.77 | EPHX1 (0.50) | L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180265547-A1 | Z-SELECTIVE OLEFIN METATHESIS OF PEPTIDES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2018-09-20 | — | — | US | disclosed |
| US-20160185821-A1 | Z-SELECTIVE OLEFIN METATHESIS OF PEPTIDES | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185821-A1 | Z-SELECTIVE OLEFIN METATHESIS OF PEPTIDES | QPCT, PTMS, MAX | CTSS 203/4885CTSK 194/4885HTT 1373/4885 |
| US-20180265547-A1 | Z-SELECTIVE OLEFIN METATHESIS OF PEPTIDES | QPCT, PTMS, MAX | CTSS 203/4885CTSK 194/4885HTT 1373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.