Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17870837 | 1.00 | ALDH1A1 (0.44) | ALDH1A1TRPV1RECQLLMNAMAPT | |
| SCHEMBL30178359 | 0.88 | ALDH1A1 (0.51) | ALDH1A1TRPV1RECQLMAPTNPC1 | |
| SCHEMBL19873697 | 0.85 | ALDH1A1 (0.45) | ALDH1A1TRPV1RECQLLMNAMAPT | |
| SCHEMBL17870704 | 0.84 | MAPT (0.39) | ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL30178389 | 0.81 | TRPV1 (0.34) | ALDH1A1TRPV1RECQLKMT2A | |
| SCHEMBL17870715 | 0.80 | ALDH1A1 (0.44) | ALDH1A1TRPV1RECQLLMNAMAPT | |
| SCHEMBL17870716 | 0.80 | ALDH1A1 (0.44) | ALDH1A1TRPV1RECQLLMNAMAPT | |
| SCHEMBL28638738 | 0.72 | ALDH1A1 (0.46) | ALDH1A1TRPV1RECQLLMNAMAPT | |
| SCHEMBL30178371 | 0.72 | ALDH1A1 (0.46) | ALDH1A1TRPV1RECQLLMNAMAPT | |
| SCHEMBL30178466 | 0.72 | ALDH1A1 (0.54) | ALDH1A1LMNAMAPTKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3237403-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2017-11-01 | — | — | EP | disclosed |
| WO-2016102882-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2016-06-30 | — | — | WO | disclosed |