SCHEMBL17870866

SCHEMBL17870866

CC(=O)SCCC(=O)O.CC(=O)SCCC(=O)O.CC(=O)SCCC(=O)O.CCC(CO)(CO)CO

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.38
TSHR P16473 2/20 0.38
KMT2A Q03164 2/20 0.37
LMNA P02545 2/20 0.37
HSD17B10 Q99714 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CYP2C19 P33261 1/20 0.35
POLB P06746 1/20 0.34
BLM P54132 1/20 0.34
ATM Q13315 1/20 0.34
HDAC3 O15379 2/20 0.33
HDAC1 Q13547 2/20 0.33
HDAC2 Q92769 2/20 0.33
HDAC8 Q9BY41 2/20 0.33
FFAR3 O14843 1/20 0.33
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
THRB P10828 1/20 0.32
SLC15A2 Q16348 1/20 0.32
HDAC4 P56524 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL668605 0.82
Succinic Acid SCHEMBL542105 0.80 LMNA (0.47) CYP1A2TSHRKMT2ALMNAHSD17B10
Hydrochloric Acid SCHEMBL4589722 0.80 TSHR (0.52) CYP1A2TSHRKMT2ALMNAHSD17B10
SCHEMBL29712334 0.79 TSHR (0.39) CYP1A2TSHRKMT2ALMNAHSD17B10
Succinic Acid SCHEMBL28597264 0.76 LMNA (0.43) CYP1A2TSHRKMT2ALMNAHSD17B10
Adipic Acid SCHEMBL7761237 0.76 AKR1B1 (0.54) TSHRKMT2ALMNAHSD17B10TDP1
SCHEMBL29793964 0.76 FFAR3 (0.42) CYP1A2TSHRKMT2ALMNAHSD17B10
Adipic Acid SCHEMBL536500 0.76 AKR1B1 (0.54) TSHRKMT2ALMNAHSD17B10TDP1
Butyric Acid SCHEMBL813982 0.76 FFAR3 (0.62) CYP1A2TSHRKMT2AHSD17B10TDP1
Adipic Acid SCHEMBL536569 0.76 AKR1B1 (0.54) TSHRKMT2ALMNAHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016102573-A1 USE OF A THIOLESTER AS A HARDENER FOR EPOXIDE ADHESIVES HENKEL AG & CO. KGAA (DE) 2016-06-30 WO disclosed