SCHEMBL17873202

SCHEMBL17873202

CC(CN(CC#N)CC#N)N(CC#N)CC#N

nearest known ligand 0.56

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.56
MAPK1 P28482 1/20 0.56
MAOB P27338 1/20 0.32
DPP4 P27487 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9976278 1.00 CYP1A2 (0.56) CYP1A2MAPK1MAOBDPP4
SCHEMBL20000110 0.77 CYP1A2 (0.90) CYP1A2MAPK1MAOBDPP4
SCHEMBL11702536 0.73 CYP1A2 (0.58) CYP1A2MAPK1DPP4
SCHEMBL236516 0.72 CYP1A2 (1.00) CYP1A2MAPK1MAOBDPP4
SCHEMBL23470298 0.71 CYP1A2 (0.39) CYP1A2MAPK1MAOBDPP4
SCHEMBL12703835 0.71 CYP1A2 (0.48) CYP1A2MAPK1MAOBDPP4
SCHEMBL20755993 0.68 CYP1A2 (0.65) CYP1A2MAPK1DPP4
SCHEMBL713835 0.68 LCK (0.38) CYP1A2MAPK1
SCHEMBL16580145 0.67 CYP1A2 (0.44) CYP1A2MAPK1MAOBDPP4
SCHEMBL1582129 0.67 CYP1A2 (0.44) CYP1A2MAPK1MAOBDPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10590064-B2 Crystals of alanine N-acetic acid precursors, process to prepare them and their use NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2020-03-17 US disclosed
CN-110804022-A Preparation method of dexrazoxane 扬子江药业集团有限公司 2020-02-18 CN disclosed
EP-3237375-B1 CRYSTALS OF ALANINE N-ACETIC ACID PRECURSORS, PROCESS TO PREPARE THEM AND THEIR USE AKZO NOBEL CHEMICALS INT BV (NL) 2019-04-10 EP disclosed
US-20170334833-A1 Crystals of Alanine N-Acetic Acid Precursors, Process to Prepare Them and Their Use NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2017-11-23 US disclosed
EP-3237375-A1 CRYSTALS OF ALANINE N-ACETIC ACID PRECURSORS, PROCESS TO PREPARE THEM AND THEIR USE Akzo Nobel Chemicals International B.V. (NL) 2017-11-01 EP disclosed
WO-2016102494-A1 CRYSTALS OF ALANINE N-ACETIC ACID PRECURSORS, PROCESS TO PREPARE THEM AND THEIR USE AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2016-06-30 WO disclosed