Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.77 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.64 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17836970 | 1.00 | ESR1 (0.77) | ESR1SERPINE1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL19046866 | 0.91 | ESR1 (0.66) | ESR1SERPINE1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL17836966 | 0.90 | ESR1 (0.87) | ESR1SERPINE1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL20920869 | 0.89 | ESR1 (0.64) | ESR1SERPINE1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL17854061 | 0.88 | ESR1 (0.66) | ESR1SERPINE1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL6731831 | 0.87 | ESR1 (1.00) | ESR1SERPINE1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL23484286 | 0.86 | ESR1 (0.69) | ESR1SERPINE1CA12CA1CA2 | |
| SCHEMBL6725413 | 0.84 | ESR1 (1.00) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL17836974 | 0.82 | ESR1 (0.55) | ESR1SERPINE1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL27255661 | 0.81 | ESR1 (0.58) | ESR1SERPINE1AKR1C4AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3237487-B1 | BIOCOMPATIBLE IODINATED DIPHENOL MONOMERS AND POLYMERS | UNIV RUTGERS (US) | 2021-02-17 | — | — | EP | disclosed |
| EP-3237487-A2 | BIOCOMPATIBLE IODINATED DIPHENOL MONOMERS AND POLYMERS | Rutgers, the State University of New Jersey (US) | 2017-11-01 | — | — | EP | disclosed |
| WO-2016103224-A2 | BIOCOMPATIBLE IODINATED DIPHENOL MONOMERS AND POLYMERS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-06-30 | — | — | WO | disclosed |