Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.55 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17836973 | 0.85 | TDP1 (0.45) | TDP1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL17836970 | 0.82 | ESR1 (0.77) | ESR1SERPINE1L3MBTL1AKR1C4AKR1C3 | |
| SCHEMBL17873233 | 0.82 | ESR1 (0.77) | ESR1SERPINE1L3MBTL1AKR1C4AKR1C3 | |
| SCHEMBL17836998 | 0.77 | TDP1 (0.42) | ESR1TDP1 | |
| SCHEMBL20920869 | 0.76 | ESR1 (0.64) | ESR1SERPINE1L3MBTL1AKR1C4AKR1C3 | |
| SCHEMBL19046866 | 0.74 | ESR1 (0.66) | ESR1SERPINE1L3MBTL1AKR1C4AKR1C3 | |
| SCHEMBL17836966 | 0.74 | ESR1 (0.87) | ESR1SERPINE1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL17854061 | 0.71 | ESR1 (0.66) | ESR1SERPINE1L3MBTL1TDP1AKR1C4 | |
| SCHEMBL17836991 | 0.71 | SMN1; SMN2 (0.36) | TDP1 | |
| SCHEMBL6731831 | 0.71 | ESR1 (1.00) | ESR1SERPINE1AKR1C4AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10087285-B2 | Biocompatible iodinated diphenol monomers and polymers | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-10-02 | — | — | US | disclosed |
| US-20160177028-A1 | BIOCOMPATIBLE IODINATED DIPHENOL MONOMERS AND POLYMERS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2016-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10087285-B2 | Biocompatible iodinated diphenol monomers and polymers | DDT, HPGDS, PTGDR | ESR1 647/4885SERPINE1 2484/4885L3MBTL1 2355/4885 |
| US-20160177028-A1 | BIOCOMPATIBLE IODINATED DIPHENOL MONOMERS AND POLYMERS | DDT, HPGDS, PTGDR | ESR1 647/4885SERPINE1 2484/4885L3MBTL1 2355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.