Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 4/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 3/20 | 0.39 |
| ▸ | DNPEP | Q9ULA0 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | F13A1 | P00488 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9973630 | 1.00 | PAOX (0.45) | PAOXKDM4EMAPK1HIF1ATSHR | |
| SCHEMBL800814 | 0.86 | — | — | |
| SCHEMBL13398529 | 0.83 | KDM4E (0.60) | PAOXKDM4EMAPK1HIF1ATSHR | |
| SCHEMBL21089233 | 0.83 | KDM4E (0.60) | PAOXKDM4EMAPK1HIF1ATSHR | |
| SCHEMBL6130978 | 0.83 | KDM4E (0.60) | PAOXKDM4EMAPK1HIF1ATSHR | |
| SCHEMBL12407913 | 0.83 | KDM4E (0.60) | PAOXKDM4EMAPK1HIF1ATSHR | |
| SCHEMBL23419326 | 0.82 | PAOX (0.43) | PAOXKDM4EMAPK1HIF1ATSHR | |
| SCHEMBL20147848 | 0.80 | ANPEP (0.41) | PAOXKDM4EMAPK1HIF1ATSHR | |
| SCHEMBL14471288 | 0.80 | KDM4E (0.46) | PAOXKDM4EMAPK1HIF1ATSHR | |
| SCHEMBL12522545 | 0.78 | PAOX (0.45) | PAOXKDM4EMAPK1HIF1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9376421-B2 | Compounds and methods for myotonic dystrophy therapy | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-06-28 | — | — | US | disclosed |