⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9973630 | 0.86 | PAOX (0.45) | — | |
| SCHEMBL17874521 | 0.86 | PAOX (0.45) | — | |
| SCHEMBL4762361 | 0.85 | KDM4E (0.61) | — | |
| SCHEMBL20147848 | 0.84 | ANPEP (0.41) | — | |
| SCHEMBL4762422 | 0.83 | KDM4E (0.65) | — | |
| SCHEMBL18478347 | 0.82 | — | — | |
| SCHEMBL6636082 | 0.82 | — | — | |
| SCHEMBL15981282 | 0.81 | KDM4E (0.70) | — | |
| SCHEMBL21227771 | 0.81 | KDM4E (0.70) | — | |
| SCHEMBL20859598 | 0.81 | KDM4E (0.70) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 243 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114557348-B | Sex attractant for bactrocera dorsalis and application thereof | 哈尔滨学院 | 2023-08-04 | — | — | CN | claimed |
| US-20220349870-A1 | Method for Detecting American Foulbrood in a Beehive | Y-Trace Pty Ltd (AU) | 2022-11-03 | — | — | US | claimed |
| EP-4022080-A1 | METHOD FOR DETECTING AMERICAN FOULBROOD IN A BEEHIVE | CRC for Honey Bee Products (AU) | 2022-07-06 | — | — | EP | claimed |
| CN-114557348-A | Sex attractant for bactrocera dorsalis and application thereof | 哈尔滨学院 | 2022-05-31 | — | — | CN | claimed |
| WO-2021062474-A1 | METHOD FOR DETECTING AMERICAN FOULBROOD IN A BEEHIVE | CRC For Honey Bee Products (AU) | 2021-04-08 | — | — | WO | claimed |
| CN-104450069-B | Environment-protective lubricant oil of oil and preparation method thereof based on bio oil | 合肥工业大学 | 2016-08-24 | — | — | CN | claimed |
| CN-104450069-A | Environment-friendly lubricating oil taking bio-oil as base oil and preparation method of lubricating oil | UNIV HEFEI TECHNOLOGY | 2015-03-25 | — | — | CN | claimed |
| US-8148537-B2 | Substituted acetophenones useful as PDE4 inhibitors | LEO PHARMA A/S (DK) | 2012-04-03 | — | — | US | claimed |
| EP-2125736-B1 | SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS | LEO PHARMA AS (DK) | 2011-03-30 | — | — | EP | claimed |
| US-20100163070-A1 | METHOD FOR STRAIGHTENING KERATINOUS FIBRES USING HEATING MEANS AND AN AMIDE | L'OREAL S.A. (FR) | 2010-07-01 | — | — | US | claimed |
| US-20100035908-A1 | SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS | LEO PHARMA (DK) | 2010-02-11 | — | — | US | claimed |
| CN-101611005-A | Be used as the acetophenones of the replacement of PDE4 inhibitor | LEO PHARMA AS (DK) | 2009-12-23 | — | — | CN | claimed |
| EP-2125736-A1 | SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS | Leo Pharma A/S (DK) | 2009-12-02 | — | — | EP | claimed |
| EP-2004193-A2 | OPHTHALMIC COMPOSITIONS FOR TREATING OCULAR HYPERTENSION | Merck & Co., Inc. (US) | 2008-12-24 | — | — | EP | claimed |
| WO-2008077404-A1 | SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS | LEO PHARMA A/S (DK) | 2008-07-03 | — | — | WO | claimed |
| CN-101198325-A | Ophthalmic compositions for treating ocular hypertension | MERCK & CO INC (US) | 2008-06-11 | — | — | CN | claimed |
| WO-2007108968-A2 | OPHTHALMIC COMPOSITIONS FOR TREATING OCULAR HYPERTENSION | MERCK & CO., INC. (US) | 2007-09-27 | — | — | WO | claimed |
| CN-101035526-A | Ophthalmic compositions for treating ocular hypertension | MERCK & CO INC (US) | 2007-09-12 | — | — | CN | claimed |
| CN-1845914-A | Ophthalmic compositions for treating ocular hypertension | MERCK & CO INC (US) | 2006-10-11 | — | — | CN | claimed |
| CN-1816530-A | ophthalmic compositions for treating ocular hypertension | MERCK & CO INC (US) | 2006-08-09 | — | — | CN | claimed |