SCHEMBL17874536

SCHEMBL17874536

Cc1cc(OCCOCCC(F)(F)P(C)(=O)O)ccc1CCc1cnc2c(N)nc3cc(CCC(=O)O)ccc3c2c1

nearest known ligand 0.91

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.91

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17874538 1.00 TLR7 (0.91) TLR7
SCHEMBL29454511 0.95 TLR7 (1.00) TLR7
SCHEMBL29413224 0.95 TLR7 (1.00) TLR7
SCHEMBL174300 0.95 TLR7 (1.00) TLR7
SCHEMBL174281 0.95 TLR7 (1.00) TLR7
SCHEMBL30575423 0.95 TLR7 (1.00) TLR7
SCHEMBL17874533 0.94 TLR7 (0.91) TLR7
SCHEMBL16751867 0.93 TLR7 (0.96) TLR7
SCHEMBL19671585 0.92 TLR7 (0.78) TLR7
SCHEMBL9282188 0.91 TLR7 (0.85) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2440245-B1 BENZONAPHTHYRIDINE-CONTAINING VACCINES GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2017-12-06 EP disclosed
US-9375471-B2 Adjuvanted formulations of booster vaccines GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2016-06-28 US disclosed