SCHEMBL17874563

SCHEMBL17874563

Cc1ccc2c(c1)nc(N)c1ncc(CCc3ccc(OCCCCCP(C)(=O)O)cc3C)cc12

nearest known ligand 0.91

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TLR7 Q9NYK1 20/20 0.91

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12841337 1.00 TLR7 (0.91) TLR7
SCHEMBL17874564 0.99 TLR7 (0.89) TLR7
SCHEMBL17874552 0.97 TLR7 (0.90) TLR7
SCHEMBL170115 0.95 TLR7 (1.00) TLR7
SCHEMBL30575443 0.95 TLR7 (1.00) TLR7
SCHEMBL1527631 0.95 TLR7 (1.00) TLR7
SCHEMBL30575428 0.95 TLR7 (1.00) TLR7
SCHEMBL173264 0.94 TLR7 (0.98) TLR7
SCHEMBL30575432 0.94 TLR7 (0.98) TLR7
SCHEMBL30575438 0.92 TLR7 (1.00) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9375471-B2 Adjuvanted formulations of booster vaccines GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2016-06-28 — — US disclosed
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