Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 7/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 13/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17875325 | 0.88 | AOC3 (0.46) | DGAT1 | |
| SCHEMBL14060367 | 0.86 | DGAT1 (0.59) | DGAT1 | |
| SCHEMBL14136851 | 0.85 | DGAT1 (0.51) | DGAT1ITGB3ITGA2B | |
| SCHEMBL16532109 | 0.76 | DGAT1 (0.43) | DGAT1 | |
| SCHEMBL17875311 | 0.75 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL14061910 | 0.75 | DGAT1 (0.54) | DGAT1 | |
| SCHEMBL16532155 | 0.75 | DGAT1 (0.41) | DGAT1 | |
| SCHEMBL17921224 | 0.74 | DGAT1 (0.61) | DGAT1 | |
| SCHEMBL16997608 | 0.74 | DGAT1 (0.46) | DGAT1ITGB3ITGA2B | |
| SCHEMBL14136646 | 0.74 | AOC3 (0.46) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2710013-B1 | NOVEL COMPOUNDS AS DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2016-06-29 | — | — | EP | disclosed |