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SCHEMBL17875406

SCHEMBL17875406

Cc1cc(Cc2cc(C)c(C)c(C(O)(C(F)(F)F)C(F)(F)F)c2)cc(C(O)(C(F)F)C(F)(F)F)c1C

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ MEN1 O00255 1/20 0.31
▸ ALOX15 P16050 1/20 0.31
▸ TSHR P16473 1/20 0.31
▸ MAPK1 P28482 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ HSD17B10 Q99714 1/20 0.31
▸ PDE4A P27815 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17875401 0.88 SMN1; SMN2 (0.40) SMN1; SMN2MEN1ALOX15TSHRMAPK1
SCHEMBL15831660 0.73 AR (0.39) —
SCHEMBL15733061 0.72 SMN1; SMN2 (0.45) SMN1; SMN2MEN1ALOX15TSHRMAPK1
SCHEMBL16838071 0.70 AR (0.36) —
SCHEMBL15958204 0.69 MEN1 (0.49) SMN1; SMN2MEN1ALOX15TSHRMAPK1
SCHEMBL17875399 0.68 SMN1; SMN2 (0.43) SMN1; SMN2MEN1ALOX15TSHRMAPK1
SCHEMBL15957881 0.68 SMN1; SMN2 (0.42) SMN1; SMN2MEN1ALOX15TSHRMAPK1
SCHEMBL15957892 0.66 SMN1; SMN2 (0.49) SMN1; SMN2MEN1ALOX15TSHRMAPK1
SCHEMBL13199118 0.63 TPMT (0.39) SMN1; SMN2ALOX15TSHRHSD17B10
SCHEMBL15958203 0.62 SMN1; SMN2 (0.50) SMN1; SMN2MEN1ALOX15TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2716351-B1 GAS SEPARATION MEMBRANE CENTRAL GLASS CO LTD (JP) 2016-06-29 — — EP disclosed