Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SHBG | P04278 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 3/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.33 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17875406 | 0.88 | SMN1; SMN2 (0.33) | SMN1; SMN2MEN1MAPK1KMT2AALOX15 | |
| SCHEMBL15831660 | 0.84 | AR (0.39) | SHBGARESR1ESR2HMGB1 | |
| SCHEMBL15733061 | 0.82 | SMN1; SMN2 (0.45) | SMN1; SMN2MEN1MAPK1KMT2AALOX15 | |
| SCHEMBL16838071 | 0.80 | AR (0.36) | SHBGARESR1ESR2HMGB1 | |
| SCHEMBL15958204 | 0.79 | MEN1 (0.49) | SMN1; SMN2MEN1MAPK1KMT2AALOX15 | |
| SCHEMBL17875399 | 0.78 | SMN1; SMN2 (0.43) | SMN1; SMN2MEN1MAPK1KMT2AALOX15 | |
| SCHEMBL15957881 | 0.77 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1MAPK1KMT2AALOX15 | |
| SCHEMBL15957892 | 0.76 | SMN1; SMN2 (0.49) | SMN1; SMN2MEN1MAPK1KMT2AALOX15 | |
| SCHEMBL13199118 | 0.71 | TPMT (0.39) | SMN1; SMN2ALOX15TSHRHSD17B10AR | |
| SCHEMBL15957883 | 0.71 | SMN1; SMN2 (0.50) | SMN1; SMN2MEN1MAPK1KMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2716351-B1 | GAS SEPARATION MEMBRANE | CENTRAL GLASS CO LTD (JP) | 2016-06-29 | — | — | EP | disclosed |