SCHEMBL17876752

SCHEMBL17876752

c1ccc(-n2c3ccccc3c3ccc4c5cc6ccccc6cc5oc4c32)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.45
ATM Q13315 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
ALDH1A1 P00352 4/20 0.37
TSHR P16473 2/20 0.37
POLB P06746 2/20 0.37
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
BRCA1 P38398 1/20 0.37
HSD17B10 Q99714 1/20 0.37
SIRT2 Q8IXJ6 1/20 0.35
SIRT1 Q96EB6 1/20 0.35
PPARG P37231 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
NR2E3 Q9Y5X4 1/20 0.33
NCOR2 Q9Y618 1/20 0.33
DYRK1A Q13627 1/20 0.32
LMNA P02545 1/20 0.32
PRKDC P78527 4/20 0.31
XRCC6 P12956 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17990688 0.90 KDM4E (0.36) KDM4EATML3MBTL1ALDH1A1TSHR
SCHEMBL19382732 0.90 KDM4E (0.33) KDM4EATML3MBTL1ALDH1A1POLB
SCHEMBL17990617 0.89 KDM4E (0.33) KDM4EATML3MBTL1ALDH1A1TSHR
SCHEMBL17990723 0.88 KDM4E (0.34) KDM4EATML3MBTL1ALDH1A1TSHR
SCHEMBL27428968 0.86 KDM4E (0.49) KDM4EATML3MBTL1ALDH1A1TSHR
SCHEMBL24357012 0.86 ALOX5 (0.38) KDM4EATML3MBTL1ALDH1A1TSHR
SCHEMBL17991032 0.85 MAPT (0.36) KDM4EATML3MBTL1ALDH1A1TSHR
SCHEMBL24356943 0.85 KDM4E (0.44) KDM4EATML3MBTL1ALDH1A1TSHR
SCHEMBL17245989 0.84 KDM4E (0.52) KDM4EATML3MBTL1ALDH1A1TSHR
SCHEMBL24357000 0.84 KDM4E (0.35) KDM4EATML3MBTL1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016105072-A2 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME 주식회사 두산 2016-06-30 WO disclosed