Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1787766 | 1.00 | HRH3 (0.46) | HRH3CYP2D6AXLALDH1A1KDM2B | |
| SCHEMBL1791740 | 1.00 | HRH3 (0.46) | HRH3CYP2D6AXLALDH1A1KDM2B | |
| SCHEMBL1792091 | 0.88 | HRH3 (0.48) | HRH3CYP2D6AXLALDH1A1KDM2B | |
| SCHEMBL1788556 | 0.85 | HRH3 (0.45) | HRH3CYP2D6KDM2B | |
| SCHEMBL1788940 | 0.84 | HRH3 (0.44) | HRH3CYP2D6AXLALDH1A1KDM2B | |
| SCHEMBL1789551 | 0.84 | HRH3 (0.47) | HRH3CYP2D6ALDH1A1KDM2B | |
| SCHEMBL1787768 | 0.84 | ALDH1A1 (0.37) | ALDH1A1GAAKMT2A | |
| SCHEMBL1791976 | 0.78 | HRH3 (0.58) | HRH3CYP2D6ALDH1A1KMT2A | |
| SCHEMBL7949457 | 0.77 | HPGD (0.48) | HRH3CYP2D6GAAKMT2A | |
| SCHEMBL1788649 | 0.77 | HPGD (0.48) | HRH3CYP2D6GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2326625-A1 | BENZAZEPINE DERIVATIVES AND THEIR USE AS HSTAMINE H3 ANTAGONISTS | Takeda Pharmaceutical Company Limited (JP) | 2011-06-01 | — | — | EP | disclosed |
| US-20110124626-A1 | BENZAZEPINE DERIVATIVES AND THEIR USE AS HISTAMINE H3 ANTAGONISTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-05-26 | — | — | US | disclosed |
| WO-2010007382-A1 | BENZAZEPINE DERIVATIVES AND THEIR USE AS HSTAMINE H3 ANTAGONISTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED. (JP) | 2010-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124626-A1 | BENZAZEPINE DERIVATIVES AND THEIR USE AS HISTAMINE H3 ANTAGONISTS | HRH4, HRH3, HRH2 | HRH3 2/4885CYP2D6 359/4885AXL 3933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.