SCHEMBL17877943

SCHEMBL17877943

c1ccc(-c2cccc3c2c2c(-c4ccc(N(c5ccccc5)c5ccc(-c6cccc7c6c6c(-c8ccccc8)cccc6n7-c6ccccc6)cc5)cc4)cccc2n3-c2ccccc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.39
L3MBTL1 Q9Y468 4/20 0.39
ATM Q13315 2/20 0.39
APP P05067 1/20 0.36
HSD17B10 Q99714 1/20 0.36
ALDH1A1 P00352 5/20 0.35
MAPT P10636 3/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ABCG2 Q9UNQ0 1/20 0.33
MAPK14 Q16539 1/20 0.32
PLK4 O00444 1/20 0.32
MAPK9 P45984 1/20 0.32
LIMK1 P53667 1/20 0.32
CLK4 Q9HAZ1 1/20 0.32
AKT3 Q9Y243 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23659236 0.93 KDM4E (0.34) KDM4EL3MBTL1ATMAPPHSD17B10
SCHEMBL23659238 0.93 KDM4E (0.34) KDM4EL3MBTL1ATMAPPHSD17B10
SCHEMBL25160838 0.93 KDM4E (0.34) KDM4EL3MBTL1ATMAPPHSD17B10
SCHEMBL26190937 0.90 KDM4E (0.34) KDM4EL3MBTL1ATMAPPABCG2
SCHEMBL17877950 0.90 L3MBTL1 (0.47) KDM4EL3MBTL1ATMAPPHSD17B10
SCHEMBL17853060 0.89 ABCG2 (0.33) KDM4EL3MBTL1ATMAPPHSD17B10
SCHEMBL26190976 0.88 KDM4E (0.35) KDM4EL3MBTL1ATMABCG2AVPR1A
SCHEMBL17877965 0.88 L3MBTL1 (0.46) KDM4EL3MBTL1ATMHSD17B10ALDH1A1
SCHEMBL17877940 0.88 L3MBTL1 (0.46) KDM4EL3MBTL1ATMAPPHSD17B10
SCHEMBL17877961 0.88 L3MBTL1 (0.46) KDM4EL3MBTL1ATMHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9985217-B2 Material for organic electroluminescent device and organic electroluminescent device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2018-05-29 US disclosed
US-9985217-B2 Material for organic electroluminescent device and organic electroluminescent device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2018-05-29 US disclosed
US-20160190468-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-30 US disclosed
US-20160190468-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160190468-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME L1CAM, ODC1, OR10J3 KDM4E 746/4885L3MBTL1 483/4885ATM 1298/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.