SCHEMBL17878956

SCHEMBL17878956

CC1(C)c2ccccc2-c2cc3c4ccccc4c4cc(-c5cc(-n6c7ccccc7c7ccccc76)cc(-n6c7ccccc7c7ccccc76)c5)ccc4c3cc21

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.33
▸ ATM Q13315 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ RXRA P19793 1/20 0.30
▸ RXRB P28702 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17878947 0.92 KDM4E (0.37) KDM4EATML3MBTL1RXRARXRB
SCHEMBL17886461 0.91 KDM4E (0.36) KDM4EATML3MBTL1
SCHEMBL18675909 0.90 KDM4E (0.33) KDM4EATML3MBTL1RXRARXRB
SCHEMBL17878941 0.90 KDM4E (0.40) KDM4EATML3MBTL1RXRARXRB
SCHEMBL17878929 0.90 — —
SCHEMBL17878925 0.90 — —
SCHEMBL17692379 0.89 KDM4E (0.36) KDM4EATML3MBTL1
SCHEMBL17692346 0.89 KDM4E (0.38) KDM4EATML3MBTL1
SCHEMBL17929483 0.88 KDM4E (0.35) KDM4EATML3MBTL1
SCHEMBL17692374 0.88 KDM4E (0.35) KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160190470-A1 ORGANIC MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORP. (TW) 2016-06-30 — — US disclosed
US-20160190470-A1 ORGANIC MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORP. (TW) 2016-06-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160190470-A1 ORGANIC MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME EBPL, ICMT, ICOSLG KDM4E 1016/4885ATM 4305/4885L3MBTL1 404/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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