Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.50 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.50 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.50 |
| ▸ | BMP1 | P13497 | 3/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 7/20 | 0.41 |
| ▸ | CTSD | P07339 | 2/20 | 0.41 |
| ▸ | GRM8 | O00222 | 1/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14553975 | 1.00 | DPP4 (0.50) | DPP4DPP8DPP9BMP1BLM | |
| SCHEMBL15451422 | 0.94 | DPP4 (0.55) | DPP4DPP8DPP9BMP1BLM | |
| SCHEMBL14669854 | 0.94 | DPP4 (0.55) | DPP4DPP8DPP9BMP1BLM | |
| SCHEMBL17915897 | 0.94 | DPP4 (0.55) | DPP4DPP8DPP9BMP1BLM | |
| SCHEMBL13467398 | 0.94 | DPP4 (0.55) | DPP4DPP8DPP9BMP1BLM | |
| SCHEMBL16297654 | 0.91 | DPP4 (0.58) | DPP4DPP8DPP9BMP1BLM | |
| SCHEMBL17192782 | 0.88 | SIRT5 (0.50) | BMP1BLMALOX15SIRT5FOLH1 | |
| SCHEMBL29706692 | 0.88 | FOLH1 (0.51) | DPP4DPP8DPP9BMP1BLM | |
| SCHEMBL29636521 | 0.88 | FOLH1 (0.51) | DPP4DPP8DPP9BMP1BLM | |
| SCHEMBL30596280 | 0.88 | FOLH1 (0.51) | DPP4DPP8DPP9BMP1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663555-B2 | Beta sheet tapes ribbons in tissue engineering | UNIVERSITY OF LEEDS (GB) | 2017-05-30 | — | — | US | disclosed |
| US-20160340392-A1 | BETA SHEET TAPES RIBBONS IN TISSUE ENGINEERING | UNIVERSITY OF LEEDS (GB) | 2016-11-24 | — | — | US | disclosed |
| US-9447151-B2 | Beta sheet tapes ribbons in tissue engineering | THE UNIVERSITY OF LEEDS (GB) | 2016-09-20 | — | — | US | disclosed |
| US-20160185824-A1 | BETA SHEET TAPES RIBBONS IN TISSUE ENGINEERING | UNIVERSITY OF LEEDS (GB) | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160340392-A1 | BETA SHEET TAPES RIBBONS IN TISSUE ENGINEERING | IAPP, TAGLN2, KRT18 | DPP4 1820/4885DPP8 1204/4885DPP9 1560/4885 |
| US-20160185824-A1 | BETA SHEET TAPES RIBBONS IN TISSUE ENGINEERING | IAPP, TAGLN2, KRT18 | DPP4 1820/4885DPP8 1204/4885DPP9 1560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.