SCHEMBL17880384

SCHEMBL17880384

O=P(c1ccccc1)(c1ccccc1)c1cc(-c2cc(-c3ccccc3)ccn2)cc(-c2ccc3ccc4cccc5ccc2c3c45)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMO Q99835 2/20 0.36
PRKDC P78527 2/20 0.34
PIM1 P11309 1/20 0.33
PLG P00747 1/20 0.33
PLAU P00749 1/20 0.33
PIK3CA P42336 1/20 0.33
SIRT2 Q8IXJ6 1/20 0.32
FDPS P14324 1/20 0.32
MET P08581 1/20 0.31
TGFBR1 P36897 2/20 0.31
KMO O15229 1/20 0.31
MAP4K4 O95819 1/20 0.31
MAPKAPK2 P49137 2/20 0.31
ERBB2 P04626 1/20 0.31
CYP1A2 P05177 1/20 0.31
FYN P06241 1/20 0.31
MAOA P21397 1/20 0.31
ACHE P22303 1/20 0.31
AHR P35869 1/20 0.31
CDK1 P06493 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17880380 0.89 CYP2C9 (0.36) SIRT2TGFBR1ERBB2CYP1A2FYN
SCHEMBL18116635 0.87 CYP1A2 (0.37) METKMOERBB2CYP1A2FYN
SCHEMBL17880382 0.86 MEN1 (0.38) SMOMETERBB2CYP1A2FYN
SCHEMBL17880381 0.86 CYP1A2 (0.38) METERBB2CYP1A2FYNMAOA
SCHEMBL17880395 0.85 KDM4E (0.36) PIK3CAERBB2CYP1A2FYNMAOA
SCHEMBL18116634 0.85 CYP1A2 (0.37) METERBB2CYP1A2FYNMAOA
SCHEMBL18133334 0.85 CYP1A2 (0.37) METKMOERBB2CYP1A2FYN
SCHEMBL31286413 0.85 CYP1A2 (0.37) METKMOERBB2CYP1A2FYN
SCHEMBL17880383 0.85 MET (0.35) METERBB2CYP1A2FYNMAOA
SCHEMBL17880394 0.84 GUSB (0.37) SMOPRKDCPIM1PLGPLAU

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9461272-B2 Organic light emitting device including light-efficiency improvement layer SAMSUNG DISPLAY CO., LTD. (KR) 2016-10-04 US disclosed
US-9461272-B2 Organic light emitting device including light-efficiency improvement layer SAMSUNG DISPLAY CO., LTD. (KR) 2016-10-04 US disclosed
US-20160190516-A1 ORGANIC LIGHT EMITTING DEVICE INCLUDING LIGHT-EFFICIENCY IMPROVEMENT LAYER SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-30 US disclosed
US-20160190516-A1 ORGANIC LIGHT EMITTING DEVICE INCLUDING LIGHT-EFFICIENCY IMPROVEMENT LAYER SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-30 US disclosed