Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 12/20 | 0.42 |
| ▸ | CTSK | P43235 | 11/20 | 0.42 |
| ▸ | CTSB | P07858 | 3/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | PTPRA | P18433 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17884338 | 0.85 | CTSS (0.46) | CTSSCTSKCTSBCTSLADORA1 | |
| SCHEMBL4295078 | 0.84 | CTSS (0.48) | CTSSCTSKCTSBCTSLADORA1 | |
| SCHEMBL28969900 | 0.83 | CTSS (0.49) | CTSSCTSKCTSBCTSLADORA1 | |
| SCHEMBL13102997 | 0.81 | CTSS (0.47) | CTSSCTSKCTSBCTSLADORA1 | |
| SCHEMBL16807987 | 0.81 | CTSS (0.47) | CTSSCTSKCTSBCTSLADORA1 | |
| SCHEMBL13970822 | 0.80 | CTSS (0.50) | CTSSCTSKCTSBCTSLADORA1 | |
| SCHEMBL15764469 | 0.80 | CTSS (0.56) | CTSSCTSKCTSBCTSL | |
| SCHEMBL23007573 | 0.78 | CTSS (0.44) | CTSSCTSKCTSBCTSLADORA1 | |
| SCHEMBL29924138 | 0.78 | PPARA (0.49) | CTSSCTSKCTSBCTSLADORA1 | |
| SCHEMBL9555099 | 0.78 | KMT2A (0.49) | CTSSCTSKCTSBCTSLADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160185821-A1 | Z-SELECTIVE OLEFIN METATHESIS OF PEPTIDES | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185821-A1 | Z-SELECTIVE OLEFIN METATHESIS OF PEPTIDES | QPCT, PTMS, MAX | CTSS 203/4885CTSK 194/4885CTSB 313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.