Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3107973 | 1.00 | ALDH1A1 (0.41) | ALDH1A1LMNATSHRKMT2AMEN1 | |
| SCHEMBL3123664 | 0.88 | ALDH1A1 (0.47) | ALDH1A1LMNATSHRKMT2AMEN1 | |
| SCHEMBL31357040 | 0.85 | ALDH1A1 (0.53) | ALDH1A1LMNATSHRKMT2AMEN1 | |
| SCHEMBL3122051 | 0.85 | ALDH1A1 (0.53) | ALDH1A1LMNATSHRKMT2AMEN1 | |
| SCHEMBL12549518 | 0.85 | ALDH1A1 (0.53) | ALDH1A1LMNATSHRKMT2AMEN1 | |
| SCHEMBL11520943 | 0.82 | TSHR (0.39) | ALDH1A1LMNATSHRTDP1SMN1; SMN2 | |
| SCHEMBL15712645 | 0.82 | TSHR (0.39) | ALDH1A1LMNATSHRTDP1SMN1; SMN2 | |
| SCHEMBL10392606 | 0.81 | TSHR (0.38) | ALDH1A1TSHRKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11336105 | 0.80 | KMT2A (0.41) | ALDH1A1LMNATSHRKMT2AMEN1 | |
| SCHEMBL7105090 | 0.79 | SMN1; SMN2 (0.46) | ALDH1A1TSHRKMT2ASMN1; SMN2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160185821-A1 | Z-SELECTIVE OLEFIN METATHESIS OF PEPTIDES | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185821-A1 | Z-SELECTIVE OLEFIN METATHESIS OF PEPTIDES | QPCT, PTMS, MAX | ALDH1A1 4444/4885LMNA 4645/4885TSHR 2378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.