Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18027905 | 0.87 | MAP3K5 (0.55) | MAP3K5MAP3K6 | |
| SCHEMBL29978259 | 0.84 | MAP3K5 (0.53) | MAP3K5MAP3K6 | |
| SCHEMBL28391289 | 0.84 | MAP3K5 (0.53) | MAP3K5MAP3K6 | |
| SCHEMBL23865350 | 0.83 | MAP3K5 (0.40) | MAP3K5MAP3K6 | |
| SCHEMBL23865466 | 0.83 | MAP3K5 (0.44) | MAP3K5MAP3K6 | |
| SCHEMBL22642547 | 0.82 | MAP3K5 (0.51) | MAP3K5MAP3K6 | |
| SCHEMBL22096504 | 0.82 | MAP3K5 (0.53) | MAP3K5MAP3K6 | |
| SCHEMBL22601537 | 0.82 | MAP3K5 (0.51) | MAP3K5MAP3K6 | |
| SCHEMBL20557293 | 0.81 | MAP3K5 (0.53) | MAP3K5MAP3K6 | |
| SCHEMBL15135934 | 0.81 | MAP3K5 (0.50) | MAP3K5MAP3K6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4276095-A2 | PROCESSES FOR PREPARING ASK1 INHIBITORS | Gilead Sciences, Inc. (US) | 2023-11-15 | — | — | EP | disclosed |
| US-11814382-B2 | Crystal form as ASK1 inhibitor and preparation method and application thereof | FUJIAN AKEYLINK BIOTECHNOLOGY CO., LTD. (CN) | 2023-11-14 | — | — | US | disclosed |
| US-11814382-B2 | Crystal form as ASK1 inhibitor and preparation method and application thereof | FUJIAN AKEYLINK BIOTECHNOLOGY CO., LTD. (CN) | 2023-11-14 | — | — | US | disclosed |
| EP-3693366-B1 | PROCESSES FOR PREPARING ASK1 INHIBITORS | GILEAD SCIENCES INC (US) | 2023-06-28 | — | — | EP | disclosed |
| US-20220135527-A1 | PROCESSES FOR PREPARING ASK1 INHIBITORS | GILEAD SCIENCES, INC. | 2022-05-05 | — | — | US | disclosed |
| EP-3825315-A1 | CRYSTAL FORM AS ASK1 INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Fujian Cosunter Pharmaceutical Co., Ltd. (CN) | 2021-05-26 | — | — | EP | disclosed |
| EP-3237404-B1 | PROCESSES FOR PREPARING ASK1 INHIBITORS | GILEAD SCIENCES INC (US) | 2020-11-11 | — | — | EP | disclosed |
| US-20200283393-A1 | PROCESSES FOR PREPARING ASK1 INHIBITORS | GILEAD SCIENCES, INC. | 2020-09-10 | — | — | US | disclosed |
| EP-3693366-A1 | PROCESSES FOR PREPARING ASK1 INHIBITORS | Gilead Sciences, Inc. (US) | 2020-08-12 | — | — | EP | disclosed |
| WO-2020015721-A1 | CRYSTAL FORM AS ASK1 INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 福建广生堂药业股份有限公司 | 2020-01-23 | — | — | WO | disclosed |
| US-20180022708-A1 | PROCESSES FOR PREPARING ASK1 INHIBITORS | GILEAD SCIENCES, INC. | 2018-01-25 | — | — | US | disclosed |
| US-9771328-B2 | Processes for preparing ASK1 inhibitors | GILEAD SCIENCES, INC. (US) | 2017-09-26 | — | — | US | disclosed |
| US-9771328-B2 | Processes for preparing ASK1 inhibitors | GILEAD SCIENCES, INC. (US) | 2017-09-26 | — | — | US | disclosed |
| US-20170233350-A1 | PROCESSES FOR PREPARING ASK1 INHIBITORS | GILEAD SCIENCES, INC. | 2017-08-17 | — | — | US | disclosed |
| US-20170233350-A1 | PROCESSES FOR PREPARING ASK1 INHIBITORS | GILEAD SCIENCES, INC. | 2017-08-17 | — | — | US | disclosed |
| US-9586933-B2 | Processes for preparing ASK1 inhibitors | GILEAD SCIENCES, INC. (US) | 2017-03-07 | — | — | US | disclosed |
| US-9586933-B2 | Processes for preparing ASK1 inhibitors | GILEAD SCIENCES, INC. (US) | 2017-03-07 | — | — | US | disclosed |
| US-20160244430-A1 | Processes for preparing ASK1 inhibitors | GILEAD SCIENCES, INC. (US) | 2016-08-25 | — | — | US | disclosed |
| US-20160244430-A1 | Processes for preparing ASK1 inhibitors | GILEAD SCIENCES, INC. (US) | 2016-08-25 | — | — | US | disclosed |
| WO-2016106384-A1 | PROCESSES FOR PREPARING ASK1 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2016-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11814382-B2 | Crystal form as ASK1 inhibitor and preparation method and application thereof | MLKL, MAP3K1, MAP3K19 | MAP3K5 9/4885MAP3K6 6/4885 |
| US-20170233350-A1 | PROCESSES FOR PREPARING ASK1 INHIBITORS | MAP3K1, MAP3K6, MAP3K7 | MAP3K5 6/4885MAP3K6 2/4885 |
| US-20200283393-A1 | PROCESSES FOR PREPARING ASK1 INHIBITORS | MAP3K1, MAP3K6, MAP3K7 | MAP3K5 6/4885MAP3K6 2/4885 |
| US-20180022708-A1 | PROCESSES FOR PREPARING ASK1 INHIBITORS | MAP3K1, MAP3K6, MAP3K7 | MAP3K5 6/4885MAP3K6 2/4885 |
| US-20160244430-A1 | Processes for preparing ASK1 inhibitors | MAP3K1, MAP3K6, MAP3K7 | MAP3K5 6/4885MAP3K6 2/4885 |
| US-20220135527-A1 | PROCESSES FOR PREPARING ASK1 INHIBITORS | MAP3K1, MAP3K6, MAP3K7 | MAP3K5 6/4885MAP3K6 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.