Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 17/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27295134 | 0.82 | TDP1 (0.38) | CYP3A4HTTMEN1USP2ALDH1A1 | |
| SCHEMBL157502 | 0.82 | POLB (0.48) | HTTMEN1LMNAMAPTKMT2A | |
| SCHEMBL30800968 | 0.82 | POLB (0.48) | HTTMEN1LMNAMAPTKMT2A | |
| SCHEMBL22648011 | 0.81 | PDK2 (0.45) | HTTLMNAMAPTPOLBAPEX1 | |
| SCHEMBL25145527 | 0.80 | HTT (0.45) | CYP3A4HTTMEN1USP2ALDH1A1 | |
| SCHEMBL14889149 | 0.79 | POLB (0.45) | HTTMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL22872219 | 0.79 | PDK2 (0.53) | CYP3A4HTTMEN1USP2ALDH1A1 | |
| SCHEMBL25137098 | 0.79 | CYP3A4 (0.56) | CYP3A4HTTMEN1USP2ALDH1A1 | |
| SCHEMBL16903531 | 0.79 | THRB (0.46) | CYP3A4HTTMEN1USP2ALDH1A1 | |
| SCHEMBL22831755 | 0.78 | HTT (0.38) | CYP3A4HTTMEN1USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160185887-A1 | POLYMERIZABLE COMPOSITION FOR HIGH-REFRACTIVE OPTICAL MATERIAL AND METHOD FOR PREPARING HIGH-REFRACTIVE OPTICAL MATERIAL | KOC SOLUTION CO., LTD. (KR) | 2016-06-30 | — | — | US | disclosed |