Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17880837 | 0.91 | KLK7 (0.44) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL25917537 | 0.84 | SMN1; SMN2 (0.50) | NPC1RAB9ASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL9127332 | 0.83 | MAPT (0.46) | NPC1RAB9ASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL27101167 | 0.83 | SAE1 (0.49) | NPC1RAB9ASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL11119637 | 0.83 | SAE1 (0.49) | NPC1RAB9ASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL17346687 | 0.83 | MAPT (0.51) | NPC1RAB9ASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL19262238 | 0.82 | SMN1; SMN2 (0.41) | NPC1RAB9ASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL12034945 | 0.81 | SMN1; SMN2 (0.56) | NPC1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL13073361 | 0.80 | RAB9A (0.56) | NPC1RAB9ASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL25917536 | 0.79 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9737607-B2 | Polymer, and pharmaceutical composition employing the same | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2017-08-22 | — | — | US | disclosed |
| US-20160184437-A1 | Polymer, and pharmaceutical composition employing the same | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160184437-A1 | Polymer, and pharmaceutical composition employing the same | PUF60, PARG, F12 | NPC1 3903/4885RAB9A 2264/4885SMN1; SMN2 2800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.