Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | EGFR | P00533 | 5/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12904066 | 0.80 | DAO (0.67) | DAORAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL2406834 | 0.78 | DAO (0.65) | DAOPOLBPTPN11GAA | |
| SCHEMBL679809 | 0.77 | DAO (1.00) | DAOSMN1; SMN2LMNAPOLBGAA | |
| SCHEMBL12904065 | 0.77 | DAO (0.62) | DAOPOLBGAA | |
| SCHEMBL1171650 | 0.76 | DAO (0.96) | DAOSMN1; SMN2LMNAPOLBGAA | |
| SCHEMBL7208136 | 0.75 | NPC1 (1.00) | DAORAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL29475123 | 0.75 | NPC1 (1.00) | DAORAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL12880134 | 0.75 | DAO (0.59) | DAORAB9ANPC1POLBGAA | |
| Hydrochloric Acid SCHEMBL16465542 | 0.74 | NPC1 (0.97) | DAORAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL12864171 | 0.73 | DAO (0.62) | DAOPOLBNSD2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9382197-B2 | Substituted hydroxamic acids and uses thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2016-07-05 | — | — | US | claimed |