SCHEMBL17886469

SCHEMBL17886469

CC1(C)c2cc3c4ccccc4c4ccccc4c3cc2-c2cnc(-c3nc(-c4ccccc4)cc(-c4ccccc4)n3)nc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 10/20 0.35
▸ KMT2A Q03164 10/20 0.35
▸ MAPT P10636 7/20 0.35
▸ HPGD P15428 6/20 0.35
▸ ALDH1A1 P00352 5/20 0.35
▸ LMNA P02545 5/20 0.34
▸ KDM4E B2RXH2 3/20 0.34
▸ TDP1 Q9NUW8 3/20 0.33
▸ TSHR P16473 2/20 0.33
▸ ATM Q13315 1/20 0.33
▸ SMN1; SMN2 Q16637 4/20 0.33
▸ ACACA Q13085 1/20 0.33
▸ NTSR1 P30989 1/20 0.33
▸ L3MBTL1 Q9Y468 2/20 0.33
▸ ADORA2A P29274 1/20 0.33
▸ ADORA1 P30542 1/20 0.33
▸ TP53 P04637 1/20 0.32
▸ POLB P06746 1/20 0.32
▸ GAA P10253 1/20 0.32
▸ IDO1 P14902 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19008878 0.81 MEN1 (0.38) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL19008870 0.80 MEN1 (0.34) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL17563619 0.78 MEN1 (0.46) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL19008884 0.78 MEN1 (0.43) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL17563625 0.77 MEN1 (0.45) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL19008897 0.77 MEN1 (0.38) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL17886475 0.77 PIN1 (0.31) —
SCHEMBL18853501 0.77 MAPT (0.38) MEN1KMT2AMAPTALDH1A1LMNA
SCHEMBL19008853 0.77 MEN1 (0.42) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL19008857 0.77 MEN1 (0.40) MEN1KMT2AMAPTHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9793493-B2 Organic material and organic electroluminescent device using the same LUMINESCENCE TECHNOLOGY CORP. (TW) 2017-10-17 — — US disclosed
US-9793493-B2 Organic material and organic electroluminescent device using the same LUMINESCENCE TECHNOLOGY CORP. (TW) 2017-10-17 — — US disclosed
US-20160190472-A1 ORGANIC MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORP. 2016-06-30 — — US disclosed
US-20160190472-A1 ORGANIC MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORP. 2016-06-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160190472-A1 ORGANIC MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME EBPL, OXA1L, HBS1L MEN1 2010/4885KMT2A 2713/4885MAPT 524/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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