Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.50 |
| ▸ | MEN1 | O00255 | 10/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.50 |
| ▸ | MAPT | P10636 | 9/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | HBB | P68871 | 1/20 | 0.48 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.47 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL178835 | 0.90 | APP (0.55) | APPALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL178872 | 0.88 | APP (0.52) | APPALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL123560 | 0.84 | APP (0.61) | APPALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL178834 | 0.83 | APP (0.47) | APPALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL10053864 | 0.82 | APP (0.88) | APPALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL6226940 | 0.82 | APP (0.88) | APPALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL10746356 | 0.82 | APP (0.58) | APPALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL10746358 | 0.82 | APP (0.58) | APPALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL9361374 | 0.81 | MEN1 (0.58) | APPALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL9361378 | 0.81 | MEN1 (0.58) | APPALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10254562-B2 | Methods for tailoring the refractive index of lenses | BATTELLE MEMORIAL INSTITUTE (US) | 2019-04-09 | — | — | US | disclosed |
| US-10018853-B2 | Methods of altering the refractive index of materials | BATTELLE MEMORIAL INSTITUTE (US) | 2018-07-10 | — | — | US | disclosed |
| US-9827088-B2 | Methods of altering the refractive index of materials | BATTELLE MEMORIAL INSTITUTE (US) | 2017-11-28 | — | — | US | disclosed |
| US-9421090-B2 | Adjustable intraocular lens | BATTELLE MEDICAL INSTITUTE (US) | 2016-08-23 | — | — | US | disclosed |
| US-20160228238-A1 | METHODS OF ALTERING THE REFRACTIVE INDEX OF MATERIALS | BATTELLE MEMORIAL INSTITUTE | 2016-08-11 | — | — | US | disclosed |
| US-20160229132-A1 | METHODS OF ALTERING OPTICAL POWER OF A LENS | BATTELLE MEMORIAL INSTITUTE | 2016-08-11 | — | — | US | disclosed |
| US-20160221283-A1 | METHODS FOR TAILORING THE REFRACTIVE INDEX OF LENSES | BATTELLE MEMORIAL INSTITUTE (US) | 2016-08-04 | — | — | US | disclosed |
| US-20160221281-A1 | LENS MODIFICATION METHODS | BATTELLE MEMORIAL INSTITUTE | 2016-08-04 | — | — | US | disclosed |
| US-20160195734-A1 | METHODS OF ALTERING THE REFRACTIVE INDEX OF MATERIALS | BATTELLE MEMORIAL INSTITUTE | 2016-07-07 | — | — | US | disclosed |
| US-20160195735-A1 | METHODS FOR TAILORING THE REFRACTIVE INDEX OF LENSES | BATTELLE MEMORIAL INSTITUTE | 2016-07-07 | — | — | US | disclosed |
| US-9232993-B2 | Adjustable intraocular lens | BATTELLE MEMORIAL INSTITUTE (US) | 2016-01-12 | — | — | US | disclosed |
| WO-2015038620-A2 | METHODS FOR TAILORING THE REFRACTIVE INDEX OF LENSES | BATTELLE MEMORIAL INSTITUTE (US) | 2015-03-19 | — | — | WO | disclosed |
| WO-2015038614-A1 | METHODS OF ALTERING THE REFRACTIVE INDEX OF MATERIALS | BATTELLE MEMORIAL INSTITUTE (US) | 2015-03-19 | — | — | WO | disclosed |
| WO-2015038623-A1 | LENS MODIFICATION METHODS | BATTELLE MEMORIAL INSTITUTE (US) | 2015-03-19 | — | — | WO | disclosed |
| WO-2015038611-A1 | METHODS OF ALTERING OPTICAL POWER OF A LENS | BATTELLE MEMORIAL INSTITUTE (US) | 2015-03-19 | — | — | WO | disclosed |
| EP-2578185-A2 | Adjustable intraocular lens | BATTELLE MEMORIAL INSTITUTE (US) | 2013-04-10 | — | — | EP | disclosed |
| US-20120268710-A1 | ADJUSTABLE INTRAOCULAR LENS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2012-10-25 | — | — | US | disclosed |
| US-20120059163-A1 | Non-linear opticaly active molecules, their synthesis, and use | OPTIMER PHOTONICS, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| WO-2009124231-A1 | ADJUSTABLE INTRAOCULAR LENS | BATTELLE MEMORIAL INSTITUTE (US) | 2009-10-08 | — | — | WO | disclosed |
| US-20080004415-A1 | Non-linear optically active molecules, their synthesis, and use | OPTIMER PHOTONICS, INC. (US) | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059163-A1 | Non-linear opticaly active molecules, their synthesis, and use | INCENP, CYBA, ADCY5 | APP 2538/4885ALDH1A1 371/4885MEN1 4480/4885 |
| US-20080004415-A1 | Non-linear optically active molecules, their synthesis, and use | INCENP, CYBA, PAICS | APP 2995/4885ALDH1A1 378/4885MEN1 4473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.