Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HBB | P68871 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17890333 | 1.00 | MAPT (0.44) | MAPTSMN1; SMN2HPGDALDH1A1IP6K1 | |
| SCHEMBL31258284 | 0.92 | KDM4E (0.43) | MAPTSMN1; SMN2HPGDALDH1A1IP6K1 | |
| SCHEMBL17890344 | 0.92 | KDM4E (0.43) | MAPTSMN1; SMN2HPGDALDH1A1IP6K1 | |
| SCHEMBL17890345 | 0.92 | KDM4E (0.43) | MAPTSMN1; SMN2HPGDALDH1A1IP6K1 | |
| SCHEMBL15624230 | 0.89 | CHAT (0.46) | MAPTSMN1; SMN2HPGDALDH1A1IP6K1 | |
| SCHEMBL27943764 | 0.85 | KDM4E (0.47) | MAPTSMN1; SMN2HPGDALDH1A1NPC1 | |
| SCHEMBL15624214 | 0.82 | CHAT (0.46) | MAPTSMN1; SMN2HPGDALDH1A1NPC1 | |
| SCHEMBL8692442 | 0.79 | KDM4E (0.50) | IP6K1CYP1A2MEN1KMT2AKDM4E | |
| SCHEMBL15624213 | 0.77 | CHAT (0.49) | MAPTSMN1; SMN2HPGDALDH1A1NPC1 | |
| SCHEMBL10708645 | 0.75 | KDM4E (0.60) | MAPTIP6K1CYP1A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9863937-B2 | Fluorescent molecular rotors | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2018-01-09 | — | — | US | disclosed |
| US-20160195519-A1 | FLUORESCENT MOLECULAR ROTORS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2016-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160195519-A1 | FLUORESCENT MOLECULAR ROTORS | DYNC1LI2, DNAH12, DYNLL2 | MAPT 2260/4885SMN1; SMN2 4781/4885HPGD 4250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.