Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHAT | P28329 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 8/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 3/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15624214 | 0.94 | CHAT (0.46) | CHATRAB9AMEN1KMT2APOLB | |
| SCHEMBL15624213 | 0.92 | CHAT (0.49) | CHATRAB9AMEN1KMT2APOLB | |
| SCHEMBL17890335 | 0.89 | MAPT (0.44) | RAB9AMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL17890333 | 0.89 | MAPT (0.44) | RAB9AMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL17905913 | 0.85 | CHAT (0.54) | CHATRAB9AMEN1KMT2APOLB | |
| SCHEMBL17890344 | 0.81 | KDM4E (0.43) | RAB9AMEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL31258284 | 0.81 | KDM4E (0.43) | RAB9AMEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL17890345 | 0.81 | KDM4E (0.43) | RAB9AMEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL10256978 | 0.77 | CHAT (0.61) | CHATRAB9AMEN1KMT2ASMN1; SMN2 | |
| Iodide SCHEMBL28417346 | 0.76 | CHAT (0.56) | CHATRAB9AMEN1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014044757-A1 | CATIONIC TRIPHENYLAMINE DERIVATIVES ACTIVABLE BY VISIBLE AND INFRA RED LIGHT FOR INDUCING AND IMAGING APOPTOSIS IN CANCER CELLS | INSTITUT CURIE (FR) | 2014-03-27 | — | — | WO | disclosed |
| EP-2711366-A1 | Cationic triphenylamine derivatives activable by visible and Infra Red light for inducing and imaging apoptosis in cancer cells | Institut Curie (FR) | 2014-03-26 | — | — | EP | disclosed |