SCHEMBL1789133

SCHEMBL1789133

C#CCOP(N)(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10935171 0.79
SCHEMBL3262560 0.79
SCHEMBL1789131 0.79 ACHE (0.39)
SCHEMBL6423255 0.79 ACHE (0.39)
Hydrochloric Acid SCHEMBL11244451 0.77 ACHE (0.38)
Hydrochloric Acid SCHEMBL11244454 0.77 ACHE (0.38)
Hydrochloric Acid SCHEMBL11243597 0.77 ACHE (0.38)
Phosphoric Acid SCHEMBL27915366 0.77 ACHE (0.38)
SCHEMBL8340923 0.75
SCHEMBL11353358 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119768186-A Lipid conjugates for delivery of therapeutic agents to CNS tissues 箭头药业股份有限公司 2025-04-04 CN disclosed
US-8183355-B2 Method for the synthesis of oligonucleotide derivatives CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2012-05-22 US disclosed
US-20110245478-A1 Method for the Synthesis of Oligonucleotide Derivatives CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) 2011-10-06 US disclosed
US-7951926-B2 Method for the synthesis of oligonucleotide derivatives CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2011-05-31 US disclosed
US-20090142849-A1 Stable Oxygen Isotope Labeling of Pre-existing Phosphoryl Groups on Phosphomolecules for Modification-Specific Mass Spectrometry UNIVERSITY OF CONNECTICUT (US) 2009-06-04 US disclosed
US-20090124571-A1 METHOD FOR THE SYNTHESIS OF OLIGONUCLEOTIDE DERIVATIVES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2009-05-14 US disclosed
EP-2021351-A2 METHOD FOR THE SYNTHESIS OF TRIAZOLE-CONTAINING OLIGONUCLEOTIDE DERIVATIVES Centre National de la Recherche Scientifique (FR) 2009-02-11 EP disclosed
WO-2007125429-A2 METHOD FOR THE SYNTHESIS OF TRIAZOLE- CONTAINING OLIGONUCLEOTIDE DERIVATIVES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2007-11-08 WO disclosed