⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17230048 | 0.80 | ACACB (0.38) | — | |
| SCHEMBL15908809 | 0.76 | CCR1 (0.39) | — | |
| SCHEMBL2428713 | 0.75 | — | — | |
| SCHEMBL153364 | 0.75 | — | — | |
| SCHEMBL31444949 | 0.75 | — | — | |
| SCHEMBL4137228 | 0.75 | — | — | |
| SCHEMBL9252734 | 0.75 | — | — | |
| SCHEMBL423307 | 0.75 | — | — | |
| SCHEMBL1922166 | 0.75 | — | — | |
| SCHEMBL30790426 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 360 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12600696-B2 | Aromatic compounds | Xeniopro GmbH (DE) | 2026-04-14 | — | — | US | disclosed |
| CN-121318987-B | 4-Chloro-1-methyl-6H-isochromeno [3,4-c ] pyridine and synthetic method and application thereof | 上海隆盛化工有限公司 | 2026-03-24 | — | — | CN | disclosed |
| CN-121318987-A | 4-Chloro-1-methyl-6H-isochromeno [3,4-c ] pyridine and synthetic method and application thereof | 上海隆盛化工有限公司 | 2026-01-13 | — | — | CN | disclosed |
| EP-4618974-A1 | OREXIN RECEPTOR AGONISTS | Merck Sharp & Dohme LLC (US) | 2025-09-24 | — | — | EP | disclosed |
| CN-116082311-B | Phthalazinone compound, preparation method and medical application thereof | 上海济煜医药科技有限公司 | 2025-04-25 | — | — | CN | disclosed |
| US-20250114374-A1 | BCL-2 INHIBITORS | NEWAVE PHARMACEUTICAL INC. | 2025-04-10 | — | — | US | disclosed |
| US-12234223-B2 | Phthalazinone compound, and preparation method therefor and medical use thereof | SHANGHAI JEMINCARE PHARMACEUTICALS CO., LTD. (CN) | 2025-02-25 | — | — | US | disclosed |
| US-20250059166-A1 | PIPERIDINYLPYRIDINYLCARBONITRILE DERIVATIVES AS INHIBITORS OF GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE AND GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE LIKE PROTEIN | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2025-02-20 | — | — | US | disclosed |
| WO-2025031917-A1 | PIPERIDINYLPYRIDINYLCARBONITRILE DERIVATIVES AS INHIBITORS OF GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE AND GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE LIKE PROTEIN | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2025-02-13 | — | — | WO | disclosed |
| CN-119176794-A | Heterocyclic compound, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2024-12-24 | — | — | CN | disclosed |
| WO-2007115643-A1 | SUBSTITUTED ENAMINOCARBONYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2007-10-18 | — | — | WO | disclosed |
| WO-2007115647-A1 | BICYCLIC ENAMINO(THIO)CARBONYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2007-10-18 | — | — | WO | disclosed |
| WO-2007115647-A1 | BICYCLIC ENAMINO(THIO)CARBONYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2007-10-18 | — | — | WO | disclosed |
| WO-2007109334-A2 | SIP RECEPTOR MODULATING COMPOUNDS AND USE THEREOF | EPIX DELAWARE, INC. (US) | 2007-09-27 | — | — | WO | disclosed |
| WO-2007109334-A2 | SIP RECEPTOR MODULATING COMPOUNDS AND USE THEREOF | EPIX DELAWARE, INC. (US) | 2007-09-27 | — | — | WO | disclosed |
| US-5475112-A | Reducing a substituted trichloromethylpyridine derivative in presence of a proton donor and solvent | ISHIHARA SANGYO KAISHA LTD. (JP) | 1995-12-12 | — | — | US | disclosed |
| EP-0512436-A1 | Method for producing substituted pyridine derivatives | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |
| US-4562009-A | Halonitriles, their preparation and use to make halopyridines | THE DOW CHEMICAL COMPANY (US) | 1985-12-31 | — | — | US | disclosed |
| US-4562009-A | Halonitriles, their preparation and use to make halopyridines | THE DOW CHEMICAL COMPANY (US) | 1985-12-31 | — | — | US | disclosed |
| EP-0143465-A2 | Novel halonitriles and their preparation | THE DOW CHEMICAL COMPANY (US) | 1985-06-05 | — | — | EP | disclosed |