⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30019862 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL27746574 | 0.97 | NOS3 (0.50) | — | |
| SCHEMBL29427127 | 0.79 | — | — | |
| SCHEMBL30017969 | 0.79 | — | — | |
| SCHEMBL165105 | 0.79 | — | — | |
| SCHEMBL153364 | 0.79 | — | — | |
| SCHEMBL221321 | 0.75 | — | — | |
| SCHEMBL1156177 | 0.75 | — | — | |
| SCHEMBL22564750 | 0.75 | — | — | |
| SCHEMBL20544775 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 259 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250049772-A1 | PIPERIDINYL-3-(ARYLOXY)PROPANAMIDES AND PROPANOATES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2025-02-13 | — | — | US | disclosed |
| WO-2024138211-A1 | PPARG INVERSE AGONISTS AND USES THEREOF | FLARE THERAPEUTICS INC. (US) | 2024-06-27 | — | — | WO | disclosed |
| US-12005054-B2 | Piperidinyl-3-(aryloxy)propanamides and propanoates | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-06-11 | — | — | US | disclosed |
| CN-112236423-B | Piperidinyl-3- (aryloxy) propanamides and propionic acid esters | 武田药品工业株式会社 | 2024-02-06 | — | — | CN | disclosed |
| US-20230338429-A1 | COMPOUNDS AND USE THEREOF IN THE EXPANSION OF STEM CELLS AND/OR PROGENITOR CELLS | UNIVERSITE DE MONTREAL (CA) | 2023-10-26 | — | — | US | disclosed |
| US-20230303552-A1 | ARYLSULFONYL DERIVATIVES AND THEIR USE AS MUSCARINIC ACETYLCHOLINE RECEPTOR M5 INHIBITORS | VANDERBILT UNIVERSITY | 2023-09-28 | — | — | US | disclosed |
| US-20230265054-A1 | PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING | GENENTECH, INC. (US) | 2023-08-24 | — | — | US | disclosed |
| US-20230265054-A1 | PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING | GENENTECH, INC. (US) | 2023-08-24 | — | — | US | disclosed |
| US-20230192607-A1 | TRANSCRIPTIONAL ENHANCED ASSOCIATE DOMAIN (TEAD) TRANSCRIPTION FACTOR INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-06-22 | — | — | US | disclosed |
| US-20230192607-A1 | TRANSCRIPTIONAL ENHANCED ASSOCIATE DOMAIN (TEAD) TRANSCRIPTION FACTOR INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-06-22 | — | — | US | disclosed |
| US-4665186-A | 2,2,4,4-tetrasubstituted 4-formylbutyronitrile intermediates for the production of trisubstituted pyridines | CIBA-GEIGY CORPORATION (US) | 1987-05-12 | — | — | US | disclosed |
| US-4508905-A | GASTRIC ACID SECRETION INHIBITORS | AKTIEBOLAGET HASSLE (SE) | 1985-04-02 | — | — | US | disclosed |
| EP-0046735-B1 | PROCESS FOR THE PREPARATION OF CHLOROPYRIDINES SUBSTITUTED WITH METHYL OR TRIFLUOROMETHYL GROUPS | CIBA-GEIGY AG (CH) | 1984-12-12 | — | — | EP | disclosed |
| US-4469896-A | Process for the production of chloropyridines substituted by methyl, trichloromethyl or trifluoromethyl groups | CIBA-GEIGY CORPORATION (US) | 1984-09-04 | — | — | US | disclosed |
| US-4359465-A | HETEROCYCLIC ALKYLSULFINYL BENZIMIDAZOLES | THE UPJOHN COMPANY (US) | 1982-11-16 | — | — | US | disclosed |
| US-4337257-A | Gastric acid secretion inhibiting substituted 2-(2-benzimidazolyl)-pyridines, their preparation, pharmaceutical preparations containing same, and method for inhibiting gastric acid secretion | AKTIEBOLAGET HASSLE (SE) | 1982-06-29 | — | — | US | disclosed |
| EP-0046735-A2 | Process for the preparation of chloropyridines substituted with methyl or trifluoromethyl groups | CIBA-GEIGY AG (CH) | 1982-03-03 | — | — | EP | disclosed |
| EP-0005129-B1 | SUBSTITUTED PYRIDYLSULFINYLBENZIMIDAZOLES HAVING GASTRIC ACID SECRETION PROPERTIES, PHARMACEUTICAL PREPARATIONS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PREPARATION | Aktiebolaget Hässle (SE) | 1981-04-29 | — | — | EP | disclosed |
| US-4255431-A | Gastric acid secretion inhibiting substituted 2-(2-benzimidazolyl)-pyridines, pharmaceutical preparations containing same, and method for inhibiting gastric acid secretion | AKTIEBOLAGET HASSLE (SE) | 1981-03-10 | — | — | US | disclosed |
| EP-0005129-A1 | Substituted pyridylsulfinylbenzimidazoles having gastric acid secretion properties, pharmaceutical preparations containing same, and intermediates for their preparation | Aktiebolaget Hässle (SE) | 1979-10-31 | — | — | EP | disclosed |