Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17893911 | 0.85 | BTK (0.42) | ALDH1A1MAPTKMT2A | |
| SCHEMBL15878300 | 0.78 | POLB (0.41) | POLBGAAALDH1A1APLNRMAPT | |
| SCHEMBL17893916 | 0.78 | POLB (0.41) | POLBGAAALDH1A1APLNRMAPT | |
| SCHEMBL15878656 | 0.74 | POLB (0.44) | POLBGAAALDH1A1MAPTKMT2A | |
| SCHEMBL15878658 | 0.74 | POLB (0.44) | POLBGAAALDH1A1MAPTKMT2A | |
| SCHEMBL11073784 | 0.69 | POLB (0.56) | POLBGAAALDH1A1MAPTKMT2A | |
| SCHEMBL17892543 | 0.68 | BTK (0.44) | POLBGAAALDH1A1KMT2AMEN1 | |
| SCHEMBL23236621 | 0.66 | POLB (0.57) | POLBGAAALDH1A1KMT2AMEN1 | |
| SCHEMBL15878151 | 0.66 | POLB (0.57) | POLBGAAALDH1A1KMT2AMEN1 | |
| SCHEMBL15878149 | 0.66 | POLB (0.57) | POLBGAAALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109221-A1 | BTK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-07-07 | — | — | WO | disclosed |