Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | DPP4 | P27487 | 3/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4034725 | 0.94 | ALDH1A1 (0.51) | ALDH1A1DPP4DPP9DPP7DPP8 | |
| SCHEMBL2449861 | 0.90 | ALDH1A1 (0.49) | ALDH1A1DPP4DPP9DPP7DPP8 | |
| SCHEMBL16695086 | 0.86 | CHRM1 (0.46) | ALDH1A1DPP4DPP9DPP7DPP8 | |
| SCHEMBL2450630 | 0.85 | ALDH1A1 (0.49) | ALDH1A1DPP4DPP9DPP7DPP8 | |
| SCHEMBL15422012 | 0.85 | CHRM1 (0.49) | ALDH1A1DPP4DPP9DPP7DPP8 | |
| Hydrochloric Acid SCHEMBL2146017 | 0.84 | CHRM1 (0.45) | ALDH1A1DPP4DPP9DPP7DPP8 | |
| Hydrochloric Acid SCHEMBL2146257 | 0.83 | CHRM1 (0.47) | ALDH1A1DPP4DPP9DPP7DPP8 | |
| Hydrochloric Acid SCHEMBL2146626 | 0.82 | CHRM1 (0.44) | ALDH1A1DPP4MAPK1BCHEMEN1 | |
| SCHEMBL5912608 | 0.82 | KMT2A (0.46) | ALDH1A1DPP4DPP9DPP7DPP8 | |
| SCHEMBL8439278 | 0.80 | ALDH1A1 (0.51) | ALDH1A1DPP4DPP9DPP7DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016106628-A1 | BTK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-07-07 | — | — | WO | disclosed |