Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17895675 | 0.92 | KMT2A (0.41) | MAPTKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL17895612 | 0.84 | CSNK1D (0.41) | MAPTALDH1A1HTTSMN1; SMN2POLB | |
| SCHEMBL17895667 | 0.79 | RAB9A (0.41) | MAPTKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL20965304 | 0.76 | MAPT (0.39) | MAPTKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL17895561 | 0.76 | RAB9A (0.36) | MAPTKMT2AALDH1A1MEN1HTT | |
| SCHEMBL17895647 | 0.76 | HCRTR1 (0.38) | MAPTALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL17895609 | 0.76 | SLC6A2 (0.39) | MAPTKMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL17895727 | 0.75 | RAB9A (0.36) | MAPTKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL17895710 | 0.75 | RAB9A (0.36) | MAPTKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL17895677 | 0.75 | RAB9A (0.36) | MAPTKMT2AALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531631-B | Methods and agents for treating diseases | 安吉昂生物医药公司 | 2021-09-03 | — | — | CN | claimed |
| CN-107531631-B | Methods and agents for treating diseases | 安吉昂生物医药公司 | 2021-09-03 | — | — | CN | disclosed |
| EP-3240778-A1 | METHODS AND AGENTS FOR TREATING DISEASE | Angion Biomedica Corp. (US) | 2017-11-08 | — | — | EP | disclosed |
| WO-2016109492-A1 | METHODS AND AGENTS FOR TREATING DISEASE | ANGION BIOMEDICA CORP (US) | 2016-07-07 | — | — | WO | disclosed |