Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.68 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | KRAS | P01116 | 2/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.40 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3861613 | 0.98 | ALOX5 (0.65) | ALOX5PTGS1PTGS2MEN1KMT2A | |
| SCHEMBL12241734 | 0.95 | ALOX5 (0.60) | ALOX5PTGS1PTGS2MEN1KMT2A | |
| SCHEMBL12927722 | 0.87 | ALOX5 (0.55) | ALOX5PTGS1PTGS2MAPTKRAS | |
| SCHEMBL9966179 | 0.85 | ALOX5 (0.53) | ALOX5PTGS1PTGS2MEN1KMT2A | |
| SCHEMBL15101429 | 0.80 | ALOX5 (0.67) | ALOX5PTGS1PTGS2MEN1KMT2A | |
| SCHEMBL1873708 | 0.79 | PTGS1 (0.65) | ALOX5PTGS1PTGS2MAPTBAZ2B | |
| SCHEMBL13877233 | 0.79 | ALOX5 (0.65) | ALOX5PTGS1PTGS2MEN1KMT2A | |
| SCHEMBL4727325 | 0.78 | MAPT (0.59) | PTGS1PTGS2MEN1KMT2AMAPT | |
| SCHEMBL17895804 | 0.78 | PTGS1 (0.68) | ALOX5PTGS1PTGS2MEN1KMT2A | |
| SCHEMBL21088049 | 0.77 | HTR2A (0.50) | ALOX5PTGS1PTGS2KRASCCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109706-A1 | FUSED POLYCYCLIC 2-PYRIDINONE ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-07-07 | — | — | WO | disclosed |