Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 11/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 5/20 | 0.36 |
| ▸ | CCND1 | P24385 | 5/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17896134 | 0.99 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10PARP1 | |
| SCHEMBL17901915 | 0.93 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10PARP1 | |
| SCHEMBL17901954 | 0.88 | PARP1 (0.41) | KDM4EALDH1A1HPGDPARP1 | |
| Hydrochloric Acid SCHEMBL17895837 | 0.87 | PARP1 (0.41) | KDM4EALDH1A1HPGDPARP1 | |
| SCHEMBL17895979 | 0.85 | PARP1 (0.44) | KDM4EALDH1A1PARP1 | |
| SCHEMBL17895996 | 0.84 | PARP1 (0.42) | KDM4EALDH1A1HPGDHSD17B10PARP1 | |
| Hydrochloric Acid SCHEMBL17896014 | 0.84 | PARP1 (0.43) | KDM4EALDH1A1PARP1 | |
| Hydrochloric Acid SCHEMBL17896025 | 0.84 | PARP1 (0.41) | KDM4EALDH1A1HPGDHSD17B10PARP1 | |
| SCHEMBL17895862 | 0.82 | KMT2A (0.40) | KDM4EALDH1A1HPGDHSD17B10PARP1 | |
| SCHEMBL17896081 | 0.80 | ALDH1A1 (0.36) | KDM4EALDH1A1HPGDHSD17B10DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109706-A1 | FUSED POLYCYCLIC 2-PYRIDINONE ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-07-07 | — | — | WO | claimed |
| WO-2016109706-A1 | FUSED POLYCYCLIC 2-PYRIDINONE ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-07-07 | — | — | WO | disclosed |