Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | CD69 | Q07108 | 2/20 | 0.53 |
| ▸ | ELANE | P08246 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PTPRB | P23467 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503312 | 0.88 | SMN1; SMN2 (0.68) | SMN1; SMN2CD69ELANECYP2C19FFAR1 | |
| SCHEMBL17896578 | 0.84 | SMN1; SMN2 (0.58) | SMN1; SMN2CD69ELANECYP2C19FFAR1 | |
| SCHEMBL4739457 | 0.82 | LDHA (0.55) | SMN1; SMN2CD69FFAR1LDHAHPGD | |
| SCHEMBL16133043 | 0.82 | SMN1; SMN2 (0.60) | SMN1; SMN2CD69ELANECYP2C19FFAR1 | |
| SCHEMBL16234209 | 0.78 | SMN1; SMN2 (0.55) | SMN1; SMN2CD69ELANECYP2C19FFAR1 | |
| SCHEMBL879177 | 0.78 | HPGD (0.51) | SMN1; SMN2FFAR1LDHAHPGDPTPRB | |
| SCHEMBL12886692 | 0.78 | FGFR1 (0.39) | CYP2C19EPHX2NR1H4LMNASCN9A | |
| SCHEMBL5325453 | 0.77 | CD69 (0.64) | SMN1; SMN2CD69ELANECYP2C19FFAR1 | |
| SCHEMBL3826501 | 0.77 | SMN1; SMN2 (0.53) | SMN1; SMN2CD69ELANECYP2C19FFAR1 | |
| SCHEMBL24116187 | 0.76 | SMN1; SMN2 (0.56) | SMN1; SMN2CD69ELANECYP2C19EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160250219-A1 | SUBSTITUTED MORPHOLINES AS MODULATORS FOR THE CALCIUM SENSING RECEPTOR | LUPIN ATLANTIS HOLDINGS SA (CH) | 2016-09-01 | — | — | US | disclosed |
| US-9382216-B2 | Substituted morpholines as modulators for the calcium sensing receptor | LUPIN LIMITED (IN) | 2016-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160250219-A1 | SUBSTITUTED MORPHOLINES AS MODULATORS FOR THE CALCIUM SENSING RECEPTOR | CASR, RYR1, RYR2 | SMN1; SMN2 661/4885CD69 4875/4885ELANE 4731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.